Melatonin dosage

Melatonin is a hormone naturally produced by the pineal gland, regulating sleep-wake cycles. In herbal medicine and nutraceuticals, it is used to promote sleep onset, improve sleep quality, or regulate circadian rhythms in cases of jet lag. It is also found in certain plants (e.g., cherries, rice, corn) and fortified products.

Melatonin dosage is essential for:

• Check the actual content in food supplements
• Validate regulatory compliance, particularly for labeling or claims
• Ensure the reproducibility of formulations
• Support the development of relaxing products, functional drinks or phytotherapeutic solutions

Analytical methods: HPLC-DAD or LC-MS/MS

Melatonin analysis is performed by high-performance liquid chromatography (HPLC) with UV detection (DAD) or by chromatography coupled with mass spectrometry (LC-MS/MS) for increased sensitivity. These methods allow the molecule to be precisely detected and quantified, even at very low concentrations (< 0.1 mg/g).

Our protocols adapt according to:

• The type of formulation (capsules, tablets, plant extracts, liquids)
• The level of precision required by the specifications
• Current product compliance standards

Analyzed matrices

Melatonin dosage is proposed for different media:

• Food supplements (capsules, tablets, lozenges)
• Fortified functional drinks
• Natural plant extracts
• Products intended for animal nutrition (relaxing or regulating formulas)
• Herbal mixtures in liquid or solid form

Applications and sectors concerned

This analysis is intended for nutraceutical manufacturers, formulators of natural relaxation products, animal nutrition professionals, and distributors of enriched phytocomplexes. It is recommended for:

• From the formulation of new products
• On the standardization of plant batches rich in melatonin
• Quality monitoring and compliance of supplements on the market

Related analyses to discover

For a complete study of your relaxing or herbal formulas, also explore:

• Free theanine (amino acid) dosage – a relaxing amino acid naturally present in green tea
• Magnoflorine dosage – plant alkaloid with sedative effects
• Dosage of trigonelline – alkaloid with neuroprotective properties
• Dosage of tryptamine – precursor of serotonin, with neuromodulatory effects

Why choose YesWeLab for melatonin testing?

Since 2020, YesWeLab has been supporting nutrition, plant-based, and dietary supplement manufacturers in managing their analyses. Thanks to our centralized digital platform and a network of ISO 17025 / COFRAC-certified partner laboratories, we offer:

• Robust analytical protocols, adapted to your requirements
• A rigorous selection of the laboratory according to your target matrices and thresholds
• A scientific team at your service to personalize services

Get a quote or contact our team

Add this service to your quote now or contact our team for a personalized study of your formulations containing melatonin.