Logan acid assay

Loganic acid (CAS 18524-94-2) is a glycosylated iridoid naturally present in several medicinal plants belonging to the Rubiaceae, Gentianaceae, and Loganiaceae families. It is notably found in extracts of Gentiana lutea, Cornus officinalis, and Strychnos nux-vomica. This acid is recognized for its anti-inflammatory, antioxidant, neuroprotective, and immunomodulatory properties, which justify its use in nutraceutical and phytotherapeutic formulations.

Why measure logan acid?

The measurement of loganic acid allows us to:

• Characterize plant extracts for therapeutic, nutritional or cosmetic use.
• Control the quality and standardization of botanical raw materials.
• Verify regulatory compliance in the event of health claims.
• Promoting functional extracts in food supplements or wellness products.

The precise measurement of this iridoid is an indicator of biological potency, particularly in anti-inflammatory or tonic extracts.

Analytical methods used

Loganic acid is quantified by HPLC-DAD (high-performance liquid chromatography with diode-array detection) or LC-MS/MS (liquid chromatography coupled to tandem mass spectrometry). These techniques allow this iridoid to be distinguished from other similar compounds present in plant matrices, while ensuring high specificity, sensitivity, and reproducibility.

Matrices analyzed

• Standardized plant extracts
• Powders of roots or aerial parts
• Herbal teas and medicinal decoctions
• Dietary supplements (capsules, tablets, liquids)
• Complex phytotherapeutic formulations

Related analyses in the YesWeLab catalog

In addition to logan acid measurement, several other analyses can be used to comprehensively characterize plant extracts and guarantee their efficacy, stability, and conformity:

• Gentiopicroside dosage
  → Another iridoid present in gentian, often measured in conjunction with loganic acid in digestive or tonic extracts.
• Total polyphenol dosage
  → Allows evaluation of the overall antioxidant potential of the extract, often associated with anti-inflammatory efficacy.

These services are available individually or integrated into customized analytical plans, tailored to the requirements of the nutraceutical, cosmetic or medicinal plant sectors.

Tailor-made expertise for your plant extracts

At YesWeLab, we provide you with a network of specialized partner laboratories, most of which are ISO 17025 certified and/or COFRAC accredited. Our partners are selected according to strict criteria of quality, technical expertise, and regulatory compliance.

Since 2020, our platform has enabled manufacturers, formulators and R&D laboratories to easily manage their analysis requests: choice of matrices, desired methods, sample tracking, receipt of digital results… everything is centralized to save you time and guarantee traceability.

Need to analyze logan acid?

YesWeLab supports you in the reliable and reproducible quantification of loganic acid and associated iridoids. We help you structure an analytical plan tailored to your extract, your quality objectives, or your regulatory constraints.

Contact our scientific team with any questions, or submit your quote request directly through our digital platform.