Kirenol Dosage

Kirenol assay quantifies this bioactive diterpene compound found in several Asian medicinal plants, including Siegesbeckia orientalis , Siegesbeckia pubescens , and Siegesbeckia glabrescens . This secondary metabolite, known for its anti-inflammatory, healing, and antioxidant properties, is used as an analytical marker in the quality control of plant extracts for nutraceutical, pharmaceutical, or cosmetic use.

The analysis of kirenol is part of a process of standardization of plant extracts , guaranteeing their effectiveness, their traceability and their regulatory compliance.

Kirenol: a bioactive diterpene of therapeutic interest

Kirenol (CAS No. 52659-56-0) is a labdane diterpene isolated primarily from species of the genus Siegesbeckia , known for their traditional use in Asian medicine. These plants are used to treat joint pain, skin inflammation, and various chronic inflammatory conditions.

Pharmacologically, kirenol has several demonstrated biological activities:

• anti-inflammatory action via inhibition of the NF-κB pathway,
• antioxidant and cell-protective properties,
• healing and tissue regenerative effects,
• immunomodulatory and neuroprotective activity.

Because of this broad range of activities, kirenol has become a marker of authenticity and biological potency for extracts of Siegesbeckia and other plants rich in bioactive diterpenes.

Objectives and interest of kirenol dosage

Kirenol dosage is essential for:

• check the active ingredient content in extracts, powders or supplements,
• standardize plant raw materials to ensure batch consistency,
• assess the stability of the compound during transformation processes,
• Siegesbeckia extracts ,
• validate claims related to the anti-inflammatory, healing or antioxidant activity of finished products.

This analysis constitutes a key step in ensuring the reproducibility of the physiological effects observed, as well as compliance with the regulatory requirements of the nutraceutical sector.

Analytical methods used

The dosage of kirenol is based on high-precision chromatographic techniques adapted to the quantification of terpene compounds:

• HPLC (high-performance liquid chromatography) : Used to separate and quantify kirenol from its specific UV absorbance profile. This method is recommended for routine checks on standardized extracts.
• LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry) : reference method offering very high sensitivity and selectivity, ideal for complex matrices such as hydroalcoholic extracts or combined formulations.

Depending on the nature of the matrix, a purification step can be applied before analysis to eliminate interferences and optimize the detection of the target compound.

For a more complete evaluation of the bioactive profile of the extracts, this analysis can be combined with other services available on the YesWeLab platform, such as the dosage of total polyphenols , the dosage of flavonoids , or the dosage of total diterpenes .

Sectors and applications of kirenol dosage

Kirenol dosage applies to several areas:

• Nutraceuticals and phytotherapy Siegesbeckia orientalis extracts used for their anti-inflammatory and joint effects.
• Natural cosmetics : quality control of plant extracts incorporated into soothing, healing and restorative treatments.
• Animal nutrition : characterization of functional ingredients from medicinal plants for their antioxidant and cell protective potential.
• Phytochemical research : identification and quantification of kirenol in new plant species or in stability studies of extracts.

This analysis can be supplemented by other services from the YesWeLab catalog related to the characterization of bioactive compounds, such as ginsenoside dosage , curcumin dosage , or resveratrol dosage . These tests provide a complete overview of the phytochemical and functional profile of plant extracts.

Carrying out analyses at YesWeLab

YesWeLab entrusts the determination of kirenol to partner laboratories with expertise in chromatography and phytochemical analysis. These laboratories have state-of-the-art HPLC and LC-MS/MS equipment, guaranteeing reliable, reproducible results that comply with international standards.

The majority of our partners are certified or accredited according to the ISO 17025 standard and the COFRAC standard, ensuring the quality and traceability of analyses.

Our scientific team supports manufacturers and formulators at every stage: choosing the analytical method, defining the control plan, interpreting results, and optimizing extraction processes. Thanks to the YesWeLab digital platform, analysis management is simplified and secure, from quotes to receiving reports.

Since 2020, many players in nutraceuticals, natural health and phytochemistry research have trusted YesWeLab for the characterization of plant extracts rich in diterpenes and other active compounds.

Technical data

• CAS No.: 52659-56-0
• Methods: HPLC, LC-MS/MS
• Expertise: Physicochemical
• Sectors of activity: Nutraceuticals, animal nutrition, plants
• Measured parameters: Kirenol and diterpene derivatives

For any specific request or need for analytical support, contact our team to obtain a personalized quote and recommendations tailored to your plant extracts.