Oryzanolen (gamma-oryzanol) dosage

Gamma-oryzanol, oryzanolen, is a mixture of bioactive compounds extracted from rice bran, primarily composed of ferulic acid esters and sterols. Recognized for its antioxidant properties, it contributes to the protection of cells against oxidative stress and is generating increasing interest in the field of cardiovascular nutrition. Its dosage is essential to ensure the standardization of extracts and guarantee the efficacy of formulations, particularly in dietary supplements targeting lipid metabolism and physical performance.

Analytical methods for the determination of gamma-oryzanol

The analysis of gamma-oryzanol is carried out by liquid chromatography, allowing for precise separation and quantification of the active fractions:

• HPLC-DAD (High Performance Liquid Chromatography with Diode Array Detection) : reference method for identifying and quantifying the main fractions of oryzanol in complex extracts.
• LC-MS (Liquid Chromatography coupled with Mass Spectrometry) : a high-sensitivity technique that allows the detection of minor compounds and the confirmation of the structure of active molecules.

These methods are similar to those used for other bioactive lipid compounds, such as the assay of phytosterols or the assay of tocopherols (vitamin E) .

Industrial and nutritional applications

The measurement of gamma-oryzanol is of interest to the nutrition and nutraceutical industries in several ways:

• Dietary supplements : formulation and standardization of products targeting cardiovascular health, cholesterol regulation and athletic performance.
• Functional nutrition : integration into nutritional powders or fortified drinks to support vitality and lipid metabolism.
• Vegetable oils : quality control and valorization of rice oils and oils enriched with bioactive compounds.
• Research and development : identification of active fractions for the optimization of extraction processes and the development of new applications.

This analysis complements other strategic controls in nutraceuticals, such as isoflavone or flavonoid assays .

Matrices analyzed for gamma-oryzanol

YesWeLab offers gamma-oryzanol assays for various matrices: rice extracts, fortified nutritional powders, functional vegetable oils, and complex dietary supplement formulations. Each matrix undergoes a specific preparation process, ensuring the accuracy and reliability of the results.

Quality and traceability issues

Gamma-oryzanol control is crucial for:

• Ensure regulatory compliance of supplements and functional formulations.
• Ensuring reproducibility between production batches is essential for consumer and distributor confidence.
• To enhance the value of rice extracts and derived products through a standardized content of active compounds.
• Support nutritional claims related to cardiovascular health and physical performance.

These challenges are similar to those encountered in monitoring other bioactive compounds, such as the measurement of fatty acids or the measurement of total polyphenols .

YesWeLab's expertise in gamma-oryzanol assay

YesWeLab leverages a network of over 200 partner laboratories in France and Europe, specializing in the analysis of bioactive compounds and accredited to ISO 17025 and COFRAC standards. Our scientific team assists you in selecting the most suitable method based on your matrices and objectives: quality control, regulatory compliance, or research and development. Our digital platform simplifies the management of your analyses: online quotes, real-time sample tracking, and rapid access to results. Since 2020, numerous manufacturers, distributors, and engineering firms have entrusted us with their analyses to ensure the quality and value of their products.

Take action

Are you developing dietary supplements, vegetable oils, or nutritional formulations enriched with bioactive compounds? Entrust your samples to YesWeLab for reliable and precise gamma-oryzanol analysis. Request a quote online now for your analyses.