Dosage of datura stramonium

Jimsonweed (Datura stramonium), also known as thorn apple, is a plant known to contain highly toxic tropane alkaloids, including atropine, scopolamine, and hyoscyamine. These substances, present in the leaves and seeds, are responsible for severe neurotoxic effects and can pose a risk to human health when they contaminate food or herbal supplements.

The analysis of alkaloids in Datura stramonium is therefore essential for food safety, nutraceuticals, and the quality control of plant extracts. This service allows for the precise detection and quantification of these compounds to prevent any health risks and ensure the compliance of products placed on the market.

Importance of Datura stramonium dosage

Tropane alkaloids from Datura stramonium are among the plant contaminants monitored by health authorities. Ingestion, even in small doses, can cause serious adverse effects such as confusion, hallucinations, tachycardia, or acute poisoning.

Their laboratory measurement is essential for:

• Guarantee the safety of food and food supplements containing plant extracts
• Comply with national and European regulations regarding plant contaminants
• Ensure the conformity of production batches and avoid product recalls
• Strengthen consumer and distributor confidence in the quality of finished products

This analysis is becoming an essential tool for manufacturers in the food, nutraceutical and phytotherapy sectors.

Analytical methods used

The analysis of Datura stramonium relies on high-precision chromatographic techniques adapted to the detection of traces of toxic alkaloids:

• LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry): the reference method for identifying and quantifying tropane alkaloids with high sensitivity, even in trace amounts.
• HPLC (high-performance liquid chromatography): used as a complementary method to separate and analyze molecules present in complex plant extracts.

These approaches allow for selective and reliable detection, adapted to regulatory requirements and quality control needs.

Matrices analyzed

The alkaloid content of Datura stramonium can be determined using various matrices, including:

• Raw or standardized plant extracts
• Plant powders and preparations
• Plant-based foods and beverages
• Food supplements containing plant extracts

This analysis applies to both raw materials and finished products in order to guarantee optimal safety at each stage of the production chain.

Industrial and regulatory applications

The presence of tropane alkaloids in food and herbal supplements is strictly regulated. Their quantification is therefore essential for:

• Secure the marketing of plant products
• Demonstrate compliance with European and international regulations
• Ensure the traceability and transparency of analyzed batches
• Enhance the scientific and commercial value of products while guaranteeing their safety

This service is particularly useful for manufacturers, distributors, design offices and research laboratories involved in the development or marketing of plant-based products.

Additional analyses available

For a comprehensive risk assessment related to plant alkaloids, YesWeLab offers associated analyses such as:

Atropine dosage
Scopolamine dosage

Nicotine dosage (plant alkaloid)

These services help to complete the analytical profile of extracts and strengthen the regulatory compliance of herbal products.

YesWeLab's expertise

YesWeLab relies on a network of partner laboratories specializing in physico-chemical and toxicological analyses, rigorously selected and mostly ISO 17025 certified and COFRAC accredited.

Since 2020, our digital platform has been supporting manufacturers, distributors and design offices in managing their analyses, by simplifying quote requests, sample tracking and results receipt.

Our scientific team makes every effort to meet the specific requirements of clients with precision, reliability and responsiveness.