Dosage of datura stramonium

Datura stramonium, also known as jimsonweed, is a plant known to contain particularly toxic tropane alkaloids, including atropine, scopolamine, and hyoscyamine. These substances, present in the leaves and seeds, are responsible for severe neurotoxic effects and can pose a danger to human health when they contaminate foodstuffs or herbal supplements.

The measurement of Datura stramonium alkaloids is therefore an essential analysis in the context of food safety, nutraceuticals and quality control of plant extracts. This service allows these compounds to be precisely detected and quantified in order to prevent any health risks and ensure the compliance of products placed on the market.

Importance of Datura stramonium dosage

Tropane alkaloids from Datura stramonium are among the plant contaminants monitored by health authorities. Their ingestion, even in small doses, can cause serious adverse effects such as confusion, hallucinations, tachycardia, or acute poisoning.

Their laboratory dosage is essential for:

• guarantee the safety of foods and food supplements containing plant extracts
• comply with national and European regulations on plant contaminants
• ensure the conformity of production batches and avoid product recalls
• strengthen the confidence of consumers and distributors in the quality of finished products

This analysis is an essential tool for food, nutraceutical and phytotherapy manufacturers.

Analytical methods used

The dosage of Datura stramonium is based on high-precision chromatographic techniques adapted to the detection of traces of toxic alkaloids:

• LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry): reference method for identifying and quantifying tropane alkaloids with high sensitivity, even in trace amounts.
• HPLC (high performance liquid chromatography): used in addition to separate and analyze molecules present in complex plant extracts.

These approaches allow selective and reliable detection, adapted to regulatory requirements and quality control needs.

Analyzed matrices

The dosage of Datura stramonium alkaloids can be carried out in various matrices, including:

• crude or standardized plant extracts
• plant powders and plant preparations
• plant-based foods and drinks
• food supplements containing plant extracts

This analysis applies to both raw materials and finished products in order to guarantee optimal safety at each stage of the production chain.

Industrial and regulatory applications

The presence of tropane alkaloids in foodstuffs and herbal supplements is strictly regulated. Their quantification is therefore essential for:

• secure the marketing of plant products
• demonstrate compliance with European and international regulations
• ensure the traceability and transparency of the batches analyzed
• scientifically and commercially promote the products by guaranteeing their safety

This service is particularly useful for manufacturers, distributors, design offices and research laboratories involved in the development or marketing of plant-based products.

Additional analyses available

For a comprehensive assessment of plant alkaloid risks, YesWeLab offers associated analyses such as:

Atropine dosage
Scopolamine dosage

Nicotine (plant alkaloid) dosage

These services help to complete the analytical profile of extracts and strengthen regulatory compliance of herbal products.

YesWeLab expertise

YesWeLab relies on a network of partner laboratories specialized in physicochemical and toxicological analyses, rigorously selected and for the most part ISO 17025 certified and COFRAC accredited.

Since 2020, our digital platform has supported manufacturers, distributors and design offices in managing their analyses, by simplifying quote requests, sample tracking and receiving results.

Our scientific team strives to meet specific customer requirements with precision, reliability and responsiveness.