Scopolamine dosage

quantifies Scopolamine analysis this tropane alkaloid, which is naturally present in certain plants of the Solanaceae (notably Datura stramonium, Atropa belladonna , and Hyoscyamus niger).
Due to its potent neuroactive (anticholinergic, sedative, and hallucinogenic), scopolamine is strictly regulated. Its measurement is essential to ensure the safety, compliance, and traceability of plant-based products.

Analytical methods

The analysis is carried out by liquid chromatography coupled with mass spectrometry (LC-MS/MS), a reference method for the detection and quantification of tropane alkaloids at very low concentrations.

• LC-MS/MS : high sensitivity, selectivity and reproducibility.
• Possibility of simultaneous dosing with other alkaloids such asatropine andhyoscyamine.
• Compliance with European guidelines (EU Regulation No. 2021/1408) relating to natural contaminants in food and supplements.

Industrial applications

Scopolamine testing is applicable in various contexts:

• Control of plant extracts used in food supplements or plant protection products.
• Monitoring of plant raw materials potentially contaminated by toxic plants (e.g., cross-contamination in batches of tea or dried herbs).
• Regulatory control for placing plant-based products on the market.
• Toxicological and pharmacognosic analysis for research and development.

Matrices analyzed

• Plant extracts (leaves, stems, seeds)
• Dietary supplements
• Infusions, herbal teas, plant powders
• Plant protection products and botanical formulations

Further analyses recommended

For complete control of plant alkaloids and contaminants, YesWeLab recommends:

• Atropine dosage : tropane alkaloid associated with scopolamine,
• Hyoscyamine assay : active isomer of atropine,
• Nicotine assay : detection of natural alkaloids in plants or extracts,
• Pyrrolizidine assay : search for other toxic plant alkaloids.

YesWeLab's expertise

YesWeLab relies on a network of partner laboratories accredited to ISO 17025 and COFRAC standards, specializing in the analysis of plant alkaloids and natural contaminants.
Thanks to our intuitive digital platform, you can centralize your analytical requests, track your samples , and access your results online with ease.

Need to control the scopolamine content in your plant extracts?
Contact our scientific team now for a precise analysis that complies with regulatory requirements.