Dimethyltryptamine assay

Dimethyltryptamine (DMT) analysis is a specialized procedure used to quantify this tryptamine-like indole alkaloid in plant matrices for research and regulatory compliance purposes . As a naturally occurring psychoactive molecule in certain plants, DMT requires a sensitive and selective analytical method. At YesWeLab, we perform DMT analysis using HPLC and LC-MS/MS , with a laboratory selected based on your specific matrix, thresholds, and regulatory requirements.

Why measure dimethyltryptamine?

DMT (CAS number 61-50-7) belongs to the tryptamine family, derived from the amino acid tryptophan. Its detection and quantification serve specific needs, without any intention of production or use:

• regulatory control and compliance: verifying the absence or content of a regulated substance in a raw material or finished product;
• academic and industrial research: characterizing the composition of plant species and traditional preparations;
• security screening: detecting contamination or falsification of a botanical extract;
• authentication: supporting the traceability and correct identification of a plant.

A reliable, traceable and defensible result is essential in these sensitive contexts.

Principle of the analysis: HPLC and LC-MS/MS

The analysis relies on separation by high-performance liquid chromatography (HPLC) followed by detection by tandem mass spectrometry (LC-MS/MS), which offers high specificity and sensitivity, even at low concentrations. LC-MS/MS confirms the molecule's identity through its characteristic transitions and distinguishes it from other tryptamines and alkaloids present in the matrix. The precise selection of conditions (sample preparation, quantification limit, validated method) is defined with our scientific team according to your objective—exploratory research or regulatory submission.

Matrices analyzed

DMT analysis is applicable to plant extracts, traditional preparations, and plant powders. Each type of sample undergoes a specific preparation method to ensure representative and reproducible quantification.

Further analyses of the catalogue

The characterization of a botanical extract generally goes beyond a single molecule. We recommend combining DMT analysis with other services from our analytical catalog :

• The dosage of tryptophan, an amino acid precursor of tryptamines;
• The assay of reserpine and the assay of quinoline derivatives (quinine, cinchonine), to broaden the alkaloid profile;
• The measurement of amyrins, other plant markers of interest;
• The measurement of impurities, essential for quality control of extracts;
• The dry matter dosage to express your results on a dry basis;
• Authenticity and naturalness analysis to secure the identification and traceability of your raw materials.

Why entrust your DMT dosage to YesWeLab?

At YesWeLab, we collaborate with a carefully selected network of laboratories, most of which are certified and/or accredited (ISO 17025, COFRAC, etc.). These laboratories are chosen based on your specific needs, the matrices to be analyzed, and the required analytical techniques or methods. Analyses of regulated substances are carried out within a strict framework, reserved for research and compliance purposes.

If you have specific requirements—quantification threshold, validated method, precise regulatory context—please specify them in your request: our scientific team will do everything possible to respond accurately and promptly. Since 2020, numerous manufacturers, distributors, and engineering firms have entrusted us with the management of their analyses, sending us their samples via our digital platform.

Request a quote for a dimethyltryptamine test

Do you need to quantify DMT in a plant extract, preparation, or powder for research or regulatory compliance? Add this analysis to your quote in just a few clicks or contact our scientific team for personalized support. We guarantee a laboratory suited to your matrix, a relevant HPLC or LC-MS/MS method, and reliable, traceable results.