Avenanthramide dosage

Avenanthramides , and soothing properties. Naturally present in oat bran, these bioactive compounds play a crucial role in protecting cells against oxidative stress and modulating the inflammatory response. Their unique profile makes them highly sought-after quality markers in the human food, cosmetics, nutraceutical, and plant bioactives research sectors. Avenanthramide analysis allows for the precise identification and quantification of the different forms of these molecules, including avenanthramides A, B, and C, each with a distinct CAS number and specific properties.

Importance of dosage

Avenanthramide analysis is a key tool for assessing the quality of oat extracts, controlling the richness of active compounds, and ensuring batch-to-batch consistency. In nutraceutical formulations, this measurement verifies the actual content of bioactive molecules, ensures compliance with functional claims, and evaluates product stability. In cosmetics, it serves as a performance indicator for soothing active ingredients intended for sensitive or irritated skin. In human food, it helps to promote oats as a functional ingredient, highlighting their natural antioxidant and anti-inflammatory benefits. The measurement can also serve as a traceability marker in oat-containing products, confirming the ingredient's authenticity and quality of origin.

Analytical methods

The analysis of avenanthramides relies primarily on high-performance liquid chromatography (HPLC) and liquid chromatography coupled with mass spectrometry (LC-MS). These techniques allow for the precise separation, identification, and quantification of the different forms of avenanthramides present in plant matrices or processed products.
HPLC is a robust and reliable method, widely used for quality control. It enables the precise detection of polyphenols thanks to optimal separation and high reproducibility of results. LC-MS, on the other hand, offers superior sensitivity and the ability to distinguish molecules even at trace levels in complex matrices. It also allows for the identification of derivatives or modified forms that may be present in oat extracts or specific formulations.

Analyzed matrices

Avenanthramide analysis can be applied to a wide variety of industrial matrices. Among the most common are oat powders, standardized plant extracts, bran-rich flours, nutraceutical ingredients, finished products (oat-based dietary supplements, plant-based drinks, nutritional bars), and cosmetic formulations incorporating soothing oat-derived active ingredients. The analysis is adaptable to both raw materials and processed products, allowing for complete control of the production cycle.

Industrial use and applications

In the nutraceutical sector, avenanthramide analysis ensures the standardization of extracts and the validation of claims related to well-being, inflammation, or cellular health. Manufacturers rely on these analyses to develop polyphenol-rich formulas, positioned as protective or anti-oxidative stress agents.
In cosmetics, these compounds are sought after for their ability to soothe skin irritations, reduce redness, strengthen the skin barrier, and improve the comfort of sensitive skin. Avenanthramide analysis ensures that formulations contain the necessary levels of active ingredients to generate the desired effect.
In human food, avenanthramides are quality indicators for oat-based products. They are associated with the recognized health benefits of this cereal, particularly in relation to the control of oxidative stress and the support of inflammatory metabolism.

YesWeLab Expertise

YesWeLab works with a network of rigorously selected laboratories chosen for their expertise in physicochemical and nutritional analyses. The majority of our partners are ISO 17025 or COFRAC certified or accredited, guaranteeing measurement quality that meets industry requirements. Depending on your needs, we select the laboratory best suited to your matrix, the required sensitivity level, and the appropriate analytical technique (HPLC or LC-MS). Our scientific team supports you from the initial specifications to the receipt and interpretation of results. Thanks to our digital platform, manufacturers, formulators, distributors, and engineering firms benefit from seamless, responsive, and centralized monitoring of all their analytical services.

Other relevant analyses from the YesWeLab catalogue

To complement the avenanthramide assay, the following analyses may be useful:

• Flavonoid dosage
• Analysis of total polyphenols
• HPLC profile of phenolic compounds