Cynarin (CAS No. 30964-13-7) is a hydroxycinnamic acid derived from caffeic acid, naturally present in artichoke leaves (Cynara scolymus). Recognized for its choleretic, hepatoprotective, and digestive properties, cynarin is widely used in the formulation of dietary supplements designed to support liver function or promote digestive elimination.
Cynarin assay is a key analysis for standardizing artichoke-based plant extracts, verifying ingredient compliance, and ensuring consistent efficacy in nutraceutical products.
Why measure cynarin levels?
Cynarin is often used as a quality marker in botanical formulations. Its dosage allows for:
- To precisely quantify the artichoke extracts used in supplements or wellness formulations
- Check the content of active ingredients claimed on the label or in the claims
- Compare supplier batches or the stability of extracts over time
- To guarantee the reproducibility of the expected effects (action on digestion, bile, liver detoxification)
The dosage is particularly recommended for players in the nutraceutical sector, distributors of plant ingredients, pharmaceutical laboratories, as well as natural health brands wishing to develop formulas based on Cynara scolymus.
Proposed analytical methods
Cynarin analysis is generally performed using two reference techniques:
- HPLC-DAD: High-performance liquid chromatography with UV detection. Allows for the specific separation and quantification of cynarin, even in the presence of other phenolic acids.
- LC-MS: liquid chromatography coupled with mass spectrometry, recommended for assays at low concentrations or in complex matrices.
These methods generally require prior hydroalcoholic or aqueous extraction depending on the nature of the product (powder, dry extract, capsule, liquid).
Matrices involved
Cynarin levels can be measured in many matrices derived from plants or finished products:
- Standardized dry extracts of artichoke
- Nutraceutical capsules, tablets or powders
- Oral solutions or herbal syrups
- Botanical ingredients for food supplements
- Raw or processed plant-based raw materials
Industrial applications
This test is particularly suited to the following uses:
- Formulation and quality control of liver and digestive supplements
- Validation of regulatory compliance (minimum content)
- Standardization of plant-based active ingredients
- Evaluation of the stability of extracts over time or under aging conditions
- Optimization of extraction processes in product R&D
Why choose YesWeLab for cynarin analysis?
At YesWeLab, we select partner laboratories specializing in phytochemistry, capable of guaranteeing accurate, reliable analysis that complies with current standards. The majority of our partners are ISO 17025 certified or COFRAC accredited, ensuring optimal traceability of results.
With our platform, you benefit from:
- Personalized support from our scientific experts
- Access to cutting-edge techniques such as LC-MS/MS or HPLC-DAD
- We offer fast processing of your requests via a simple and intuitive digital tool
- Comprehensive and actionable reports for your quality, marketing, or regulatory files
Recommended internal links
To complement your analytical strategy regarding phenolic acids and plant extracts for liver function, you can also consult:
- Chlorogenic acid assay – another phenolic derivative present in artichoke
- Total polyphenol analysis – for a comprehensive assessment of antioxidant capacity
- Silymarin dosage – milk thistle extract used in combination with artichoke for liver health
Contact our team
Since 2020, YesWeLab has been supporting companies in the nutraceutical and phytotherapeutic sectors with the centralized management of their laboratory analyses. Our goal: to save you time, secure your product launches, and guarantee the quality of your plant-based formulations.
Need a quote? Contact us today via our platform.
