Wogonin Dosage

Wogonin is a bioactive flavone extracted from the root of Scutellaria baicalensis , an iconic medicinal plant in Asian pharmacopoeia, also known as Baikal skullcap. This molecule is widely studied for its anti-inflammatory, antioxidant, neuroprotective, and anxiolytic effects, making it a preferred ingredient in soothing nutraceutical and cosmetic formulations.

Wogonin is often standardized in extracts to ensure consistent effectiveness of skullcap products. Accurate dosage is therefore a major challenge for manufacturers of supplements, plant extracts, and dermo-cosmetic treatments with soothing and anti-aging properties.

Analysis methods: HPLC-DAD and LC-MS

The analysis of wogonin is based on liquid chromatography methods capable of separating, identifying and quantifying this flavone in often complex matrices:

• HPLC-DAD (diode array detection): standard method for the determination of wogonin in plant extracts and simple formulations.
• LC-MS (liquid chromatography coupled with mass spectrometry): recommended for low concentration samples or matrices enriched in similar polyphenolic compounds.

These techniques also allow, upon request, to distinguish wogonin from its structural analogues such as baicalein, baicalin or norwogonin, also present in Scutellaria baicalensis .

Why dose wogonine?

The dosage of wogonin is a key step for:

• Standardize skullcap extracts used in nutraceutical or cosmetic products.
• Guarantee the effectiveness and consistency of formulations with a soothing or anti-aging effect.
• Promote health and wellness claims, particularly in Asian markets, or supplements targeting stress and the nervous system.
• Meet quality, traceability and regulatory compliance requirements (particularly in the case of export).
• Detect fraud or overdoses, in the event of mixing with lower quality standardized extracts.

Affected matrices

Our analytical protocols are suitable for a wide variety of wogonin-containing products, including:

• Dry or fluid extracts of Scutellaria baicalensis
• Micronized root powders
• Food supplements in the form of capsules, tablets, sticks or sachets
• Soothing infusions and herbal teas
• Cosmetic formulations (serums, creams, lotions with a calming or anti-inflammatory effect)

Each matrix is ​​subject to specific preparation (extraction, purification, filtration) ensuring optimal quantification of the molecule.

Sectors of application

The dosage of wogonin is of interest to many industrial players:

• Nutraceuticals: anti-stress products, sleep, chronic inflammation, cognitive health
• Cosmetics: soothing, anti-redness, anti-aging dermo-cosmetics
• Botanical extract industry: quality control of batches, standardization of raw or enriched extracts
• Research and development: pharmacological studies, synergistic effects with other flavonoids

Expert laboratories for your plant extracts

At YesWeLab, we select laboratories specialized in phytochemistry and flavonoid analysis, with recognized expertise in the field of Asian and European plant extracts. Our partners are mostly ISO 17025 certified and have the latest chromatography equipment (HPLC-DAD, LC-MS/MS).

Depending on your goals, we help you:

• Choose the method best suited to your matrix
• Define detection and quantification thresholds that meet your specifications
• Check the compliance of your products with regulatory or marketing requirements

A platform to simplify your analyses

Since 2020, YesWeLab has supported manufacturers via a centralized digital platform, enabling them to:

• Easily manage your quote requests
• Track the progress of your analyses
• Access your reports and data online
• Interact with our scientific team for any technical details

We provide tailored, rapid and rigorous support at every stage of your project.

Further analyses recommended

• Dosage of baicalein (Scutellaria baicalensis)
• Total flavonoids assay 

Request your personalized quote now

Add this service to your online quote or contact our scientific team for any specific requests. YesWeLab is your trusted partner for the analysis and standardization of your wogonin-based plant extracts.