Tetracycline and tylosin dosage

Tetracyclines and tylosin are antibiotics commonly used in veterinary medicine to prevent or treat bacterial infections. Their intensive use in livestock farming can lead to residues in food products of animal origin such as meat, milk, eggs, and fish. These residues, strictly regulated within the European Union, must be monitored to ensure food safety and limit the risks associated with antibiotic resistance. Therefore, measuring tetracycline and tylosin levels is an essential step for the food industry.

Analytical methods for the determination of tetracyclines and tylosin

The analysis of these antibiotics relies on sensitive, multi-residue techniques:

• HPLC (high-performance liquid chromatography), used to separate different molecules and obtain overall quantification.
• LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry), the reference technique for detecting and quantifying these compounds at very low concentrations.

These methods meet the requirements of Regulation (EC) No 37/2010, which sets maximum residue limits (MRLs) in foodstuffs. They are comparable to those used for the determination of sulfonamides or streptomycins , which are also essential for the sanitary control of animal products.

Industrial and regulatory applications

Tetracycline and tylosin assays are relevant to several industrial contexts:

• Human food: verification of the conformity of meats, eggs, fish and dairy products.
• Animal production: control of veterinary practices and compliance with waiting periods before slaughter or collection.
• Distribution and export: compliance with international regulations and customer specifications.
• Research laboratories: monitoring the impact of antibiotic treatments on the quality of animal products.

These analyses are essential to secure the supply chains and reassure consumers.

Matrices analyzed for tetracyclines and tylosin

YesWeLab supports the analysis of these antibiotics in various matrices: fresh and processed meats, fish and seafood, eggs, milk and dairy products. Each matrix is ​​prepared according to a specific protocol to guarantee the reliability and reproducibility of the results.

Quality and compliance issues

The presence of tetracycline and tylosin residues raises several major issues:

• Protecting public health by reducing exposure to antibiotics.
• Preventing antimicrobial resistance, a global health problem.
• Strict adherence to the MRLs defined by European regulations.
• Maintaining the competitiveness of animal sectors through rigorous traceability and control.

These issues are similar to those addressed in the context of nitrosamine or heavy metal testing , which also contribute to food safety.

YesWeLab's expertise in measuring antibiotic residues

YesWeLab relies on a network of over 200 partner laboratories in France and Europe, accredited to ISO 17025 and COFRAC standards. Our experts will guide you in choosing the method best suited to your matrices and needs (quality control, regulatory compliance, certification, or export). Thanks to our digital platform, you benefit from a simplified and rapid service: online quote requests, sample tracking, and results delivered within optimized timeframes. Since 2020, numerous manufacturers and distributors have entrusted us with their residue analyses to guarantee the safety of their supply chains.

Take action

Do you want to test your food products for tetracyclines and tylosin? Entrust your analyses to YesWeLab for accurate, fast, and compliant results. Request a quote online today.