Tetandrin dosage

Tetandrine is a natural bisbenzylisoquinoline alkaloid primarily extracted from the root of Stephania tetrandra . Known for its potential pharmacological properties, this molecule is attracting increasing interest in the nutraceutical sector. It is being studied in particular for its anti-inflammatory, immunomodulatory, and neuroprotective effects, as well as for its potential role in regulating blood pressure via vasodilatory mechanisms.

Tetandrin analysis is essential to ensure the quality, conformity, and safety of plant extracts or formulations containing this active ingredient. This analysis verifies the active ingredient content in raw or finished products, ensures the safety of preparations for human use, and meets the standardization requirements in force in the food supplement industry.

Analytical methods used for the quantification of tetandrin

Tetandrin analysis is performed by high-performance liquid chromatography (HPLC) or by liquid chromatography-mass spectrometry (LC-MS). In some cases, diode array detection (HPLC-DAD) can be used for improved specificity in complex extracts.

The methods are adapted to different plant matrices, whether dry extracts, root powders, or herbal capsules. The use of LC-MS allows for the precise quantification of low concentrations of tetandrine, including in the presence of other similarly structured alkaloids, such as fangchine or cepharanthine, also found in Stephania spp .

Affected matrices

• Standardized plant extracts (medicinal plants, dried roots)
• Powders or capsules based on Stephania tetrandra
• Complex nutritional supplements
• Botanical products enriched with alkaloids

Industrial Applications and Challenges

Tetandrin assay is particularly strategic in the following areas:

• Nutraceutical formulation: validation of the biological activity of plant extracts.
• Quality control: identification of the target molecule in production batches.
• R&D: pharmacological studies on cardiovascular, anti-inflammatory or neuroprotective activity.
• Regulatory traceability: in response to increasing requirements on the active ingredients of food supplements and herbal products.

Tailor-made analytical expertise with YesWeLab

YesWeLab connects you with specialized partner laboratories, accredited to ISO 17025 or COFRAC, selected according to your analytical criteria, matrices, and regulatory requirements. Our digital platform allows you to centralize your analytical needs and easily manage your samples, from quote to results receipt.

We can also assist you with other commonly dosed plant alkaloids, such as:

• Colchicine dosage (toxic plants)
• Dosage of galegine Galega officinalis extract )
• Glabridine dosage (licorice extract)

These services can be combined with additional analyses of plant extracts, such as:

• Analysis of total polyphenol content
• Analysis of antioxidant activity (DPPH, ABTS)

Entrust us with your tetandrin analyses

Since 2020, numerous manufacturers, dietary supplement brands, and research firms have entrusted us with the management of their analyses through our network of laboratories and our unique platform. To receive a personalized quote or to speak with our scientific team, simply complete the online request.