Tetandrin dosage

Tetandrine is a natural bisbenzylisoquinoline alkaloid extracted primarily from the root of Stephania tetrandra . Known for its potential pharmacological properties, this molecule is attracting increasing interest in the nutraceutical sector. It is particularly studied for its anti-inflammatory, immunomodulatory, neuroprotective effects, as well as for its potential role in the regulation of blood pressure via vasodilatory mechanisms.

Tetandrin measurement is essential to ensure the quality, compliance, and safety of plant extracts or formulations containing this active ingredient. The analysis allows for verification of the active ingredient content in raw or finished products, to secure preparations for human use, and to meet the standardization requirements in force in the food supplement industry.

Analytical methods used for the quantification of tetandrin

Tetandrin analysis is performed by high-performance liquid chromatography (HPLC) or liquid chromatography-mass spectrometry (LC-MS). In some cases, diode array detection (HPLC-DAD) can be used for greater specificity in complex extracts.

The methods are suitable for different plant matrices, whether dry extracts, root powders, or herbal capsules. The use of LC-MS allows for the accurate determination of low concentrations of tetandrine, even in the presence of other similarly structured alkaloids, such as fangchine or cepharanthine, also present in Stephania spp .

Affected matrices

• Standardized plant extracts (medicinal plants, dry roots)
• Powders or capsules based on Stephania tetrandra
• Complex nutritional supplements
• Botanical products enriched with alkaloids

Industrial applications and challenges

The dosage of tetandrin is particularly strategic in the following areas:

• Nutraceutical formulation: validation of the biological activity of plant extracts.
• Quality control: identification of the target molecule in production batches.
• R&D: pharmacological studies on cardiovascular, anti-inflammatory or neuroprotective activity.
• Regulatory traceability: in response to increasing requirements for active ingredients in food supplements and herbal products.

Tailor-made analytical expertise with YesWeLab

YesWeLab connects you with specialized partner laboratories, ISO 17025 or COFRAC accredited, selected according to your analytical criteria, matrices, and regulatory constraints. Thanks to our digital platform, you can centralize your analysis needs and easily manage your samples, from quotes to results.

We can also assist you with other commonly dosed plant alkaloids, such as:

• Colchicine dosage (toxic plants)
• Dosage of galegine Galega officinalis extract )
• Glabridin (licorice extract)

These services can be combined with additional analyses on plant extracts, such as:

• Analysis of total polyphenol content
• Analysis of antioxidant activity (DPPH, ABTS)

Entrust us with your tetandrin analyses

Since 2020, numerous manufacturers, dietary supplement brands, and design offices have entrusted us with the management of their analyses through our network of laboratories and our unique platform. To receive a personalized quote or speak with our scientific team, simply complete your request online.