Stachydrine dosage

Stachydrine determination is a key step in the quality control of medicinal plant extracts, particularly those from motherwort ( Leonurus japonicus ) or other plants rich in natural alkaloids. Used as a standardization marker, stachydrine is known for its cardiovascular, sedative and tonic properties. At YesWeLab, we offer stachydrine analysis mainly by LC-MS (liquid chromatography coupled with mass spectrometry), or by HPLC as needed, to ensure reliable quantification even at very low concentrations.

What is stachydrine?

Stachydrine (CAS: 471-87-4) is a naturally occurring proline betaine alkaloid found in several plant species including Leonurus japonicus (motherwort), Citrus spp., and Stachys spp. It is widely studied for its hypotensive, cardioprotective, antioxidant, and neuroactive effects. In traditional Asian medicine, stachydrine is used as an active component in preparations for female reproductive health and cardiovascular regulation.

In modern formulation, its presence is exploited in:

• food supplements for circulatory or soothing purposes,
• phytotherapeutic formulations incorporating standardized extracts of medicinal plants,
• natural functional products enhancing their content of active plant ingredients.

Interest in stachydrine dosage

The dosage of stachydrine allows:

• Standardize plant extracts to ensure a consistent concentration of active ingredients,
• Authenticate the botanical origin of a plant extract or powder,
• Check the conformity of raw materials for gentle therapeutic purposes,
• Monitor the stability of formulations over time,
• Meet regulatory requirements for quality control.

This dosage is therefore essential for manufacturers and formulators wishing to secure and enhance their natural products.

Available analytical methods

YesWeLab offers stachydrine testing using the following techniques:

• LC-MS: preferred method for its high sensitivity and specificity, ideal for detecting stachydrine in complex matrices or in very low concentrations.
• HPLC-DAD: possible alternative in simple matrices, when the contents are sufficient for reliable UV detection.

The selection of the method will depend on the matrix to be analyzed, the desired detection thresholds and the regulatory or normative context of your product.

Commonly analyzed matrices

Our partner laboratories can measure stachydrine in a wide range of matrices:

• Dry or hydroalcoholic extracts of Leonurus japonicus or other plants,
• Raw or standardized vegetable powders,
• Food supplements in the form of capsules, tablets or liquid solutions,
• Herbal blends for cardiovascular or relaxing purposes.

Each method is validated according to rigorous protocols, in compliance with the requirements of the ISO 17025 standard.

Sectors of application

The dosage of stachydrine is aimed at industry professionals:

• Nutraceuticals: manufacturers of herbal supplements,
• Phytotherapy: natural formulation laboratories,
• Quality control: validation of raw materials or finished products,
• R&D: characterization of active ingredients in the context of developing new health products.

It is also recommended to combine this assay with other phytochemical markers for a complete profile. For example, discover our analyses of rhoeadine for calming extracts, or rosmarinic acid for plants with antioxidant activity.

Why choose YesWeLab?

Since 2020, YesWeLab has been supporting professionals in the plant and nutraceutical industries with their analytical projects. We rely on a network of accredited laboratories (ISO 17025, COFRAC, etc.), selected based on the matrix, the required analytical technique, and your regulatory needs.

Thanks to our digital platform, you can easily manage your analysis requests, track your samples, and receive results. Our scientific team advises you throughout the process to ensure reliable and usable results.

Get your personalized quote

Do you want to measure stachydrine in a plant extract or natural formulation? Our team will help you determine the best method and recommend a laboratory that meets your specific needs.