Dosage of schisandrin A, schisandrin B

Schisandrin A and Schisandrin B are bioactive lignans characteristic of the plant Schisandra chinensis , a traditional medicinal berry in Asian pharmacopoeia. These compounds are recognized for their adaptogenic, antioxidant and hepatoprotective properties , contributing to Schisandra's reputation as a general tonic and liver protector. Their dosage constitutes an essential marker to ensure the quality and authenticity of plant extracts intended for the nutraceutical or cosmetic market.

Interest in the dosage of schisandrin A and B

Quantification of these lignans is essential for several reasons:

• Standardization of plant extracts: guarantee a consistent content of active ingredients from one batch to another.
• Quality control: verify the authenticity of raw materials and prevent the risk of fraudulent substitution.
• Efficacy assessment: supporting health claims related to the properties of Schisandra (antioxidant, hepatoprotective, adaptogenic).
• Stability monitoring: monitor the evolution of schisandrin concentration in formulations over time.

Analytical methods

The analyses are based on high-performance chromatography techniques adapted to the quantification of these complex molecules:

• HPLC-UV/DAD: separation and detection of schisandrins A and B in crude extracts.
• LC-MS/MS: Trace level identification and quantification thanks to increased sensitivity, suitable for complex matrices such as capsules, powders and concentrated extracts.

These methods guarantee reliable, reproducible measurement that complies with industrial and regulatory requirements.

Analyzed matrices

The dosage of schisandrins A and B can be carried out in:

• Dry or liquid extracts of Schisandra chinensis.
• Standardized vegetable powders.
• Nutraceutical capsules and tablets.
• Cosmetic formulations enriched with natural antioxidants.

Industrial applications

The applications of dosage are numerous:

• Quality validation of Schisandra extracts.
• Development of targeted nutraceutical products (liver health, vitality, general well-being).
• Integration into anti-aging and antioxidant cosmetic treatments.
• Support for regulatory compliance and marketing approaches promoting the scientific effectiveness of products.

Related analyses in the YesWeLab catalog

The dosage of schisandrins can be supplemented by other analyses of bioactive plant compounds:

• Dosage of rutin , a vasoprotective flavonoid.
• Dosage of sakuranetin , an antioxidant and anti-inflammatory flavanone.
• Dosage of salidroside , adaptogenic phenolic glycoside extracted from Rhodiola.
• Dosage of protodioscin , saponin with stimulating and energetic effects.

These additional analyses make it possible to fully characterize botanical extracts and meet the requirements of the nutraceutical and cosmetic industries.

YesWeLab Expertise

YesWeLab provides its network of partner laboratories, rigorously selected and certified (ISO 17025, COFRAC). Our team helps you choose the most suitable analytical method , taking into account the matrices, regulatory thresholds and quality objectives of your projects. Thanks to our intuitive digital platform , you can centralize your requests, track your samples in real time and access your results quickly.