Schisandrin A and Schisandrin B assays

Schisandrin A and Schisandrin B are bioactive lignans characteristic of the Schisandra chinensis , a traditional medicinal berry in Asian pharmacopoeia. These compounds are recognized for their adaptogenic, antioxidant, and hepatoprotective properties , contributing to Schisandra's reputation as a general tonic and liver protectant. Their concentration is an essential marker for ensuring the quality and authenticity of plant extracts intended for the nutraceutical or cosmetic markets.

Importance of measuring schisandrin A and B

Quantifying these lignans is essential for several reasons:

• Standardization of plant extracts: ensuring a homogeneous content of active ingredients from one batch to another.
• Quality control: verifying the authenticity of raw materials and preventing the risks of fraudulent substitution.
• Efficacy assessment: supporting health claims related to the properties of Schisandra (antioxidant, hepatoprotective, adaptogenic).
• Stability monitoring: monitoring the evolution of schisandrin concentration in formulations over time.

Analytical methods

The analyses rely on high-performance chromatography techniques adapted to the quantification of these complex molecules:

• HPLC-UV/DAD: separation and detection of schisandrins A and B in crude extracts.
• LC-MS/MS: identification and quantification at trace levels thanks to increased sensitivity, suitable for complex matrices such as capsules, powders and concentrated extracts.

These methods guarantee reliable, reproducible measurement that complies with industrial and regulatory requirements.

Analyzed matrices

The measurement of schisandrins A and B can be performed in:

• Dry or liquid extracts of Schisandra chinensis.
• Standardized vegetable powders.
• Nutraceutical capsules and tablets.
• Cosmetic formulations enriched with natural antioxidants.

Industrial applications

The applications of dosage are numerous:

• Quality validation of Schisandra extracts.
• Development of targeted nutraceutical products (liver health, vitality, general well-being).
• Integration into anti-aging and antioxidant cosmetic treatments.
• Support for regulatory compliance and marketing efforts that highlight the scientific effectiveness of products.

Related analyses in the YesWeLab catalog

The measurement of schisandrins can be supplemented by other analyses of bioactive plant compounds:

• Rutin dosage , a vasoprotective flavonoid.
• Dosage of sakuranetin , an antioxidant and anti-inflammatory flavanone.
• Assay of salidroside , an adaptogenic phenolic glycoside extracted from Rhodiola.
• Dosage of protodioscin , a saponin with stimulating and energizing effects.

These additional analyses allow for a complete characterization of botanical extracts and meet the requirements of the nutraceutical and cosmetic industries.

YesWeLab Expertise

YesWeLab provides access to its network of rigorously selected and certified partner laboratories (ISO 17025, COFRAC). Our team assists you in choosing the most suitable analytical method , taking into account the matrices, regulatory thresholds, and quality objectives of your projects. Thanks to our intuitive digital platform , you can centralize your requests, track your samples in real time, and access your results quickly.