Rutin dosage

Rutin, also called rutinoside or sophorin, is a glycosylated flavonoid naturally present in many medicinal and food plants. It is found in particular in buckwheat, Japanese pagoda tree, citrus fruits, apples and green tea. It is particularly appreciated for its antioxidant , vasoprotective and anti-inflammatory , which makes it a marker of major interest in the field of nutraceuticals and functional cosmetics.

This compound plays a protective role with respect to the cardiovascular system and helps limit oxidative stress. Its dosage is crucial for standardizing plant extracts, validating the content of claimed active ingredients and ensuring the conformity of marketed formulations.

Interest in rutin dosage

The dosage of rutin meets several needs:

• Quality control of plant raw materials used in the nutraceutical industry.
• Validation of the efficacy and compliance of a food supplement enriched with flavonoids.
• Evaluation of the stability of cosmetic formulations containing antioxidant extracts.
• Detection of natural variability of botanical extracts and verification of their authenticity.

Analytical methods

Rutin analysis is performed mainly by high-performance liquid chromatography (HPLC) coupled with UV-Vis detection, or by mass spectrometry (LC-MS) for more precise and specific quantification, particularly in complex matrices.

• HPLC -UV is used for routine analysis and standardization of extracts.
• LC -MS/MS allows confirmation of compound identity and sensitive detection even at low concentrations.

These methods guarantee precise quantification, essential to meet traceability and regulatory compliance requirements.

Affected matrices

Rutin can be dosed in a wide variety of matrices:

• Medicinal plants : buckwheat, sophora, citrus fruits, tea.
• Plant extracts : powders, hydroalcoholic solutions, tinctures.
• Food supplements : capsules, tablets, liquid formulations.
• Cosmetic products : serums, antioxidant creams, dermocosmetic formulations.

Regulatory issues

In the nutraceutical sector, rutin measurement helps ensure product compliance with health claims and labeling. In the cosmetics sector, it meets the quality and safety requirements of formulations with protective and antioxidant properties.

In addition, the standardization of extracts rich in flavonoids such as rutin is an essential criterion for manufacturers to ensure consistent effectiveness from one batch to another.

Related analyses in the YesWeLab catalog

Rutin dosage is often carried out in addition to other analyses targeting flavonoids and polyphenols:

• Dosage of quercetin (aglycone of rutin, major antioxidant).
• Determination of total flavonoids for overall quantification of polyphenols.
• Dosage of chlorogenic acid often present in the same plant extracts.
• Catechin dosage for tea and other antioxidant-rich matrices.

YesWeLab expertise

At YesWeLab, we work with a network of laboratories selected for their expertise and accreditation (ISO 17025, COFRAC). We select the partner best suited to your needs, based on your matrices and regulatory requirements.

Our digital platform simplifies the management of your analyses: requesting quotes, tracking samples, and receiving centralized results. Since 2020, numerous manufacturers, distributors, and design offices have entrusted us with their analyses, benefiting from our scientific support and responsiveness.