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Reserpine dosage

Reserpine dosage

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

50-55-5

Description

Reserpine assay is a crucial analysis for the quality control of medicinal plant extracts, especially those from Rauwolfia serpentina . This indole alkaloid is known for its hypotensive, calming and antipsychotic effects. Its assay allows for the verification of the conformity, stability and efficacy of many nutraceutical and phytotherapeutic formulations. YesWeLab offers this assay using state-of-the-art techniques such as high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) , ensuring accurate detection, even at trace levels.

Why analyze reserpine?

Initially used in traditional Indian medicine to treat hypertension and nervous disorders, reserpine has entered modern pharmacopoeia for its sedative, antihypertensive, and antipsychotic effects. It is now present in certain natural food supplements or standardized plant extracts, particularly for the regulation of stress and sleep.

Reserpine dosage is essential in several industrial contexts:

  • Standardization of plant extracts to ensure a constant concentration of active ingredients,
  • Regulatory compliance verification in food supplements containing alkaloid plants,
  • Quality control of raw materials based on Rauwolfia serpentina (dried roots, powders, hydroalcoholic extracts),
  • Stability studies and aging tests on finished formulations.

Analytical methods: HPLC and LC-MS

HPLC It is recommended for routine quantitative analyses on controlled matrices.

LC -MS , which is more sensitive and selective, is used when the matrix is ​​complex or the reserpine concentration is low. This method also allows the identification of other co-extracted alkaloids for a more complete analysis of the phytocompound profile.

YesWeLab selects the most appropriate method based on your sample, the required detection threshold and regulatory or normative requirements.

Analyzed matrices

We perform the dosage of reserpine on different matrices, including:

  • Dry extracts of Rauwolfia serpentina ,
  • Dried root powders,
  • Food supplements in the form of capsules, tablets or liquids,
  • Herbal blends for calming purposes.

Our partner laboratories have high-precision equipment and validated protocols to guarantee reliable and reproducible results, in accordance with the requirements of ISO 17025 standards.

Sectors concerned

This analysis is primarily aimed at industry players:

  • Nutraceuticals (manufacturers and formulators of herbal supplements),
  • Phytotherapy and scientific herbalism,
  • Medicinal plant industry,
  • Design offices and specialized distributors.

Reserpine assays can also be integrated into multi-compound analyses for complex extracts containing other alkaloids or flavonoids. For example, see our fact sheets on yohimbine assays or total flavonoids , which are often found in neuroactive plant extracts.

Why go through YesWeLab?

At YesWeLab, we provide you with a carefully selected network of partner laboratories , specialized in the physicochemical and nutritional analyses of plants and active ingredients. These laboratories are mostly certified and/or accredited (ISO 17025, COFRAC) and chosen according to your specific needs: matrix, method, detection thresholds or regulatory requirements.

Since 2020, many manufacturers, formulators and distributors have entrusted us with their analyses via our digital platform, which simplifies sample management, service monitoring and access to results.

Need a quote or advice?

Do you want to measure reserpine in a plant-based raw material or dietary supplement? Describe your needs or send us your technical specifications. Our scientific team will guide you toward the most suitable analytical solution as quickly as possible.

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