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Reserpine dosage

Reserpine dosage

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

50-55-5

Description

Reserpine analysis is crucial for quality control of medicinal plant extracts, particularly those derived from Rauwolfia serpentina . This indole alkaloid is known for its hypotensive, calming, and antipsychotic effects. Its measurement allows verification of the conformity, stability, and efficacy of numerous nutraceutical and phytotherapeutic formulations. YesWeLab offers this analysis using cutting-edge techniques such as high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) , ensuring precise detection even at trace levels.

Why analyze reserpine?

Originally used in traditional Indian medicine to treat hypertension and nervous disorders, reserpine has been incorporated into modern pharmacopoeia for its sedative, antihypertensive, and antipsychotic effects. It is now found in some natural dietary supplements or standardized plant extracts, particularly for stress and sleep regulation.

Reserpine dosage is essential in several industrial contexts:

  • Standardization of plant extracts to ensure a constant concentration of active ingredients,
  • Regulatory compliance verification for food supplements containing alkaloid plants,
  • Quality control of raw materials based on Rauwolfia serpentina (dried roots, powders, hydroalcoholic extracts),
  • Stability studies and aging tests on finished formulations.

Analytical methods: HPLC and LC-MS

HPLC allows for precise separation of compounds present in complex mixtures, with UV detection adapted for reserpine. It is recommended for routine quantitative analyses on well-controlled matrices .

LC -MS , which is more sensitive and selective, is used when the matrix is ​​complex or the reserpine concentration is low. This method also allows for the identification of other co-extracted alkaloids for a more complete analysis of the phytocompound profile.

YesWeLab selects the most appropriate method based on your sample, the required detection threshold and regulatory or normative requirements.

Analyzed matrices

We perform reserpine assays on various matrices, including:

  • Dry extracts of Rauwolfia serpentina ,
  • Dried root powders,
  • Dietary supplements in the form of capsules, tablets or liquids,
  • Calming herbal blends.

Our partner laboratories have high-precision equipment and validated protocols to guarantee reliable and reproducible results, in accordance with the requirements of ISO 17025 standards.

Sectors concerned

This analysis is primarily aimed at industry stakeholders:

  • Nutraceuticals (manufacturers and formulators of herbal supplements),
  • Phytotherapy and scientific herbalism,
  • Medicinal plant industry,
  • Design offices and specialist distributors.

Reserpine analysis can also be included in a multi-component analysis for complex extracts containing other alkaloids or flavonoids. For example, see our fact sheets on yohimbine or total flavonoid , which are often found together in extracts of neuroactive plants.

Why go through YesWeLab?

At YesWeLab, we offer you a rigorously selected network of partner laboratories specializing in the physicochemical and nutritional analyses of plants and active ingredients. Most of these laboratories are certified and/or accredited (ISO 17025, COFRAC) and chosen according to your specific needs: matrix, method, detection thresholds, or regulatory requirements.

Since 2020, many manufacturers, formulators and distributors have entrusted us with their analyses via our digital platform, which simplifies sample management, service tracking and access to results.

Need a quote or advice?

Do you need to measure reserpine in a plant-based raw material or a dietary supplement? Describe your needs or provide your technical specifications. Our scientific team will guide you toward the most suitable analytical solution as quickly as possible.

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