Progoitrin (glucosinolate) dosage

Progoitrin is a naturally occurring glucosinolate found in various plants of the Brassicaceae family, particularly rapeseed and mustard seeds. These sulfur compounds are known for their role in plant defense, but some, such as progoitrin, require special monitoring due to their potential effects on thyroid function when consumed in excess .

Progoitrin measurement is essential in the development of plants for nutraceutical and agri-food use. It helps ensure the safety of plant raw materials, standardize extracts, and assess the conformity of finished products.

Analytical methods

Progoitrin analysis is based on sensitive and reliable methods, adapted to complex plant matrices:

• HPLC (high performance liquid chromatography) with UV detection, often used for the separation and quantification of glucosinolates.
• LC-MS/MS (liquid chromatography coupled with mass spectrometry) , allowing very specific detection and precise quantification, even at trace levels.

These techniques offer robust and reproducible results, essential for nutrition and health manufacturers.

Affected matrices

Progoitrin assay can be performed on a wide range of matrices:

• Rapeseed and mustard seeds.
• Oilseed cakes from the crushing of oilseeds.
• Concentrated plant extracts.
• Finished nutraceutical products or functional ingredients.

Industrial and scientific applications

Progoitrin analysis has many strategic applications:

• Food and nutritional safety : assessment of the content of potentially goitrogenic compounds in raw materials.
• Animal nutrition : monitoring of glucosinolates in rapeseed meal to ensure the safety of formulations intended for livestock.
• Standardization of plant extracts : essential for food supplements based on Brassicaceae.
• Research and innovation : scientific studies aimed at better understanding the role of glucosinolates and developing optimized plant varieties.

Related analyses

The progoitrin dosage can be supplemented by other glucosinolate and plant compound analyses available in the YesWeLab catalog:

• Glucosinolate dosage
• Goitrin and progoitrin (glucosinolate) dosage
• Total polyphenol assay to characterize complementary antioxidant properties.

Regulations and issues

The control of glucosinolates such as progoitrin is governed by food safety standards, particularly for plant-based foods and formulations intended for animal feed. These analyses are essential to demonstrate regulatory compliance and ensure consumer safety.

In a context where naturalness and transparency are becoming arguments for differentiation, controlling progoitrin content allows manufacturers to enhance their products while minimizing toxicological risks.

YesWeLab expertise

YesWeLab provides a network of partner laboratories, rigorously selected and for the most part ISO 17025 and/or COFRAC accredited. Analytical methods are adapted to your matrices and validated according to the most demanding standards.

Our scientific team supports you in the choice of techniques, the interpretation of results and the integration of these analyses into your quality control processes or your research studies.