Dosage of vascin (peganin)

The dosage of vascine , also known as peganine, is a targeted analysis to quantify this active plant alkaloid extracted from medicinal plants such as Adhatoda vasica (vasaka) and Peganum harmala . Long used in Ayurvedic medicine and traditional pharmacopoeias, vascine is recognized for its bronchodilator, expectorant and anti-inflammatory properties. It is one of the major active ingredients in plant extracts for respiratory purposes. Its dosage is essential to ensure the quality, efficacy and safety of phytotherapeutic products.

Analytical techniques: HPLC and LC-MS for reliable quantification

YesWeLab offers the measurement of vascine using two reference chromatographic methods:

• HPLC (high-performance liquid chromatography): an effective method for the separation and quantification of vascine in plant extracts or supplements, with UV or DAD detection.
• LC-MS (liquid chromatography coupled with mass spectrometry): high-sensitivity technique, ideal for complex matrices or ultra-trace assays.

These techniques allow us to verify the presence and concentration of vascine in various finished products, extracts or raw materials. Analyses are carried out in ISO 17025 accredited laboratories or according to validated methods, guaranteeing the reliability of the results.

Why analyze the vaccine?

The dosage of vascine makes it possible to respond to several technical and regulatory challenges:

• Standardize plant extracts containing Adhatoda vasica or Peganum harmala to ensure a constant concentration of active ingredient.
• Check the quality and authenticity of raw materials, particularly when importing exotic plants.
• Ensure the compliance of products containing alkaloids, to comply with current regulations and exposure thresholds.
• Optimize phytotherapeutic formulations for respiratory or antitussive purposes.
• Prepare regulatory files, particularly for food supplements or natural health products.

Matrices concerned by this analysis

The dosage of vascine can be carried out on various samples:

• Hydro-alcoholic or aqueous plant extracts
• Dried leaf or root powders
• Raw raw materials from Adhatoda vasica or Peganum harmala
• Food supplements in capsules, tablets, syrups or infusions
• Multi-extract formulations for respiratory purposes

The analysis can be adapted to simple or complex matrices, depending on the level of precision expected.

Areas of application

This analysis is particularly useful for professionals in the following sectors:

• Nutraceuticals : development and control of products based on medicinal plants used for respiratory comfort.
• Traditional herbal medicine : validation of standardized or raw extracts in formulas inspired by Ayurvedic or Unani medicine.
• Plant extract industry : verification of conformity of imported or locally produced batches.
• Scientific and clinical research : pharmacological studies on plant alkaloids and their biological activity.

Laboratories specializing in plant alkaloids

At YesWeLab, we select the most suitable partner laboratory for each project, based on your technical, regulatory, and logistical requirements. We rely on a network of laboratories specialized in plant physical chemistry, ISO 17025 accredited, and equipped for alkaloid analysis by HPLC and LC-MS.

Our services also include sample preparation, method validation and scientific support if necessary.

Centralized analysis management via our platform

Thanks to our digital platform, you can:

• Submit your analysis request online
• Track the progress of your samples
• Receive your results in a professional and usable format
• Speak with our scientific team to interpret the data or adjust your needs

Our solution is aimed at manufacturers, formulators, laboratories, importers or distributors of medicinal plants wishing to outsource their analyses under conditions of optimal reliability, traceability and speed.

Get a quote today

Add this analysis to your quote or contact our scientific team. YesWeLab has been supporting you since 2020 in the rigorous management of your analytical projects, with tailor-made services adapted to the requirements of the herbal medicine and natural health industries.