Dosage of vascin (peganin)

Vascine analysis , also known as peganine, is a targeted test used to quantify this active plant alkaloid extracted from medicinal plants such as Adhatoda vasica (vasaka) and Peganum harmala . Long used in Ayurvedic medicine and traditional pharmacopoeias, vascine is recognized for its bronchodilator, expectorant, and anti-inflammatory properties. It is one of the major active ingredients in plant extracts intended for respiratory use. Its measurement is essential to ensure the quality, efficacy, and safety of phytotherapeutic products.

Analytical techniques: HPLC and LC-MS for reliable quantification

YesWeLab offers vascin assay using two reference chromatographic methods:

• HPLC (high-performance liquid chromatography): an effective method for the separation and quantification of vascin in plant extracts or supplements, with UV or DAD detection.
• LC-MS (liquid chromatography coupled with mass spectrometry): a highly sensitive technique, ideal for complex matrices or ultra-trace assays.

These techniques allow for the verification of the presence and concentration of vascin in various finished products, extracts, or raw materials. Analyses are performed in ISO 17025 accredited laboratories or according to validated methods, guaranteeing the reliability of the results.

Why analyze the vasculature?

Vascin measurement helps address several technical and regulatory challenges:

• Standardize plant extracts containing Adhatoda vasica or Peganum harmala to ensure a constant concentration of active ingredient.
• Check the quality and authenticity of raw materials, especially when importing exotic plants.
• Ensuring the compliance of products containing alkaloids, in order to comply with current regulations and exposure thresholds.
• Optimize phytotherapeutic formulations for respiratory or antitussive purposes.
• Prepare regulatory files, particularly for food supplements or natural health products.

Matrices involved in this analysis

Vascin levels can be measured on various samples:

• Hydro-alcoholic or aqueous plant extracts
• Powders of dried leaves or roots
• Raw raw materials from Adhatoda vasica or Peganum harmala
• Dietary supplements in capsules, tablets, syrups or infusions
• Multi-extract formulations for respiratory purposes

The analysis can be adapted to simple or complex matrices, depending on the level of precision expected.

Areas of application

This analysis is particularly useful for professionals in the following sectors:

• Nutraceuticals : development and control of products based on medicinal plants used for respiratory comfort.
• Traditional phytotherapy : validation of standardized or raw extracts in formulas inspired by Ayurvedic or Unani medicine.
• Plant extracts industry : verification of the conformity of imported or locally produced batches.
• Scientific and clinical research : pharmacological studies on plant alkaloids and their biological activity.

Laboratories specializing in plant alkaloids

At YesWeLab, we select the most suitable partner laboratory for each project, based on your technical, regulatory, and logistical requirements. We rely on a network of laboratories specializing in plant physicochemical analysis, accredited to ISO 17025, and equipped for alkaloid analysis by HPLC and LC-MS.

Our services also include sample preparation, method validation and scientific support if necessary.

Centralized analytics management via our platform

Thanks to our digital platform, you can:

• Submit your analysis request online
• Track the progress of your samples
• Receive your results in a professional and usable format
• Discuss the data with our scientific team to interpret the data or adjust your needs

Our solution is aimed at manufacturers, formulators, laboratories, importers or distributors of medicinal plants wishing to outsource their analyses under optimal conditions of reliability, traceability and speed.

Get a quote today

Add this analysis to your quote or contact our scientific team. YesWeLab has been supporting you since 2020 in the rigorous management of your analytical projects, with customized services tailored to the requirements of the phytotherapy and natural health industries.