Oryzanol (gamma-oryzanol) dosage

Gamma-oryzanol, oryzanolen, is a mixture of bioactive compounds extracted from rice bran, primarily consisting of ferulic acid esters and sterols. Known for its antioxidant properties, it contributes to the protection of cells against oxidative stress and is attracting increasing interest in the field of cardiovascular nutrition. Its dosage is essential to ensure the standardization of extracts and the effectiveness of formulations, particularly in dietary supplements targeting lipid metabolism and physical performance.

Analytical methods for the determination of gamma-oryzanol

The analysis of gamma-oryzanol is carried out by liquid chromatography, allowing precise separation and quantification of the active fractions:

• HPLC-DAD (High Performance Liquid Chromatography with Diode Array Detection) : reference method for identifying and measuring the main fractions of oryzanol in complex extracts.
• LC-MS (Liquid Chromatography coupled with Mass Spectrometry) : high sensitivity technique allowing the detection of minority compounds and confirmation of the structure of active molecules.

These methods are similar to those used for other bioactive lipid compounds, such as the determination of phytosterols or the determination of tocopherols (vitamin E) .

Industrial and nutritional applications

The dosage of gamma-oryzanol has several interests for the nutrition and nutraceutical industries:

• Dietary supplements : formulation and standardization of products targeting cardiovascular health, cholesterol regulation and athletic performance.
• Functional nutrition : integration into nutritional powders or fortified drinks to support vitality and lipid metabolism.
• Vegetable oils : quality control and valorization of rice oils and oils enriched with bioactive compounds.
• Research and development : identification of active fractions for the optimization of extraction processes and the development of new applications.

This analysis complements other strategic controls in nutraceuticals, such as the dosage of isoflavones or the dosage of flavonoids .

Matrices analyzed for gamma-oryzanol

YesWeLab handles gamma-oryzanol assays in a variety of matrices: rice extracts, enriched nutritional powders, functional vegetable oils, and complex dietary supplement formulations. Each matrix is ​​specifically prepared, ensuring accurate and reliable results.

Quality and traceability issues

Control of gamma-oryzanol is crucial for:

• Ensure regulatory compliance of supplements and functional formulations.
• Guarantee reproducibility between production batches , essential for consumer and distributor confidence.
• Enhance rice extracts and derived products with a standardized content of active compounds.
• Support nutritional claims related to cardiovascular health and physical performance.

These issues are similar to those encountered in the monitoring of other bioactive compounds, such as the dosage of fatty acids or the dosage of total polyphenols .

YesWeLab's expertise in gamma-oryzanol dosage

YesWeLab relies on a network of more than 200 partner laboratories in France and Europe, specialized in the analysis of bioactive compounds and accredited by ISO 17025 and COFRAC. Our scientific team helps you choose the most suitable method according to your matrices and your objectives: quality control, regulatory compliance, or research and development. Thanks to our digital platform, managing your analyses is simplified: online quotes, real-time sample tracking, and quickly accessible results. Since 2020, many manufacturers, distributors, and design offices have entrusted us with their analyses to secure the quality and value of their products.

Take action

Are you developing dietary supplements, vegetable oils, or nutritional formulations enriched with bioactive compounds? Entrust your samples to YesWeLab for reliable and accurate gamma-oryzanol testing. Request a quote online now for your analyses.