Menthofuran Dosage

Menthofuran is a natural aromatic compound belonging to the oxygenated monoterpene , found in certain essential oils of mint (Mentha piperita, Mentha pulegium). It contributes to the characteristic mint scent, with sweet and slightly fruity notes.
this compound also has hepatotoxic potential when present in high concentrations, particularly in oils rich in pulegone, of which it is a metabolite.

The dosage of menthofuran is therefore essential for:

• Evaluate the quality and safety of natural essential oils,
• To control the purity and conformity of food or cosmetic flavorings,
• Prevent toxicological risks associated with excessive levels of potentially harmful monoterpenes.

Analytical methods used

At YesWeLab , the analysis of menthofuran relies on high-precision chromatographic techniques, adapted to the complexity of plant and aromatic matrices.

The main methods used are:

• GC-FID (gas chromatography with flame ionization detection) : used for the quantification of menthofuran in essential oils or volatile formulations.
• GC-MS (gas chromatography coupled with mass spectrometry) : reference method allowing specific identification and qualitative and quantitative analysis of menthofuran in complex products (flavors, cosmetics, extracts).

ISO 11024 and AFNOR NF T75-006 standards , guaranteeing the reproducibility and traceability of the results.

Regulatory and toxicological context

Menthofuran is regulated at the European level due to its potential liver toxicity . It is listed in the European Commission's guidelines (Regulation (EC) No 1334/2008) on food flavorings and natural substances.
Its use is restricted in cosmetic and food products , particularly when derived from peppermint or pennyroyal essential oils.

The permitted thresholds vary according to the matrix and type of product , and laboratory testing makes it possible to certify the conformity of batches to IFRA (International Fragrance Association) and REACH regulations.

Industrial applications of menthofuran dosage

Menthofuran assay is an essential tool for several industrial sectors:

• Aromatherapy and essential oils : control of the chemical composition of batches, validation of botanical origin, detection of alterations or contamination.
• Cosmetics industry : verification of menthofuran concentrations in creams, balms, dental gels or massage products containing mint extracts.
• Agri-food and nutraceuticals : securing natural flavors used in chewing gums, drinks, supplements or diet products.
• Research and quality control : monitoring the chemical stability of essential oils during storage or processing.

Affected matrices

• Mint essential oils (piperita, pulegium, arvensis, spicata)
• Natural food flavorings
• Plant extracts and nutraceutical products
• Perfumed cosmetics (lotions, toothpastes, gels)

Recommended Related Analyses

For a complete assessment of the quality and safety of essential oils, YesWeLab recommends combining this analysis with other complementary tests:

• Pulegone dosage : monitoring of the toxic precursor of menthofuran, present in mints and certain aromatic herbs.
• Menthol dosage : determination of the main active compound responsible for the cooling effect,
• Methyleugenol assay : detection of another aromatic compound subject to IFRA restriction,
• SVHC test – substances of very high concern : REACH compliance check for regulated substances.

Why entrust your analysis to YesWeLab?

Since 2020, YesWeLab has been supporting professionals in the nutraceutical, cosmetic, and plant protection sectors with their analytical needs.
Through a network of ISO 17025/COFRAC accredited partner laboratories , YesWeLab offers:

• Reliable and standardized analyses ,
• A choice of methods adapted to each matrix ,
• Centralized management via its digital platform ,
• Personalized scientific support to interpret results and ensure regulatory compliance.

Need to test the menthofuran content in your essential oils or cosmetic products?
YesWeLab today for a personalized quote and certified results that meet international standards.