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MDI (diphenylmethane diisocyanate) dosage

MDI (diphenylmethane diisocyanate) dosage

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

9016-87-9

Method

Description

MDI (diphenylmethane diisocyanate) is a chemical compound widely used in the manufacture of polyurethane foams, adhesives, coatings, and composite materials. It is classified as a sensitizing and potentially toxic substance, and its measurement is crucial for assessing exposure, verifying regulatory compliance (REACH, workplace safety), or monitoring residues in finished materials. Analysis is generally performed by liquid chromatography (HPLC) after derivatization of isocyanate groups, often coupled with UV detection or mass spectrometry (LC-MS). This measurement applies to polymers, paints, adhesives, technical textiles, or air samples collected in the workplace.

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