Luteolin dosage

Luteolin is a natural flavone with remarkable biological properties, present in many medicinal and aromatic plants such as thyme, artichoke, celery, rosemary or chamomile. It is recognized for its antioxidant, anti-inflammatory, antiviral and neuroprotective effects, which makes it a marker of major interest for the formulation of food supplements, standardized extracts and herbal products.

Luteolin dosage is essential to guarantee the quality of plant extracts, verify the content of active ingredients, or to carry out stability and regulatory compliance studies in the nutraceutical, cosmetic or phytotherapeutic fields.

Analytical method: HPLC-DAD or LC-MS/MS

Luteolin analysis is performed by HPLC (high performance liquid chromatography) with diode array detection (DAD) or by LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry), depending on the level of sensitivity or complexity of the matrices.

The steps include:

• Extraction of phenolic compounds from dry or liquid matrices
• Optimized chromatographic separation
• Specific and sensitive detection, allowing the quantification of free luteolin even at low concentrations

All methods are deployed in ISO 17025 accredited partner laboratories and comply with COFRAC standards, ensuring the reliability and traceability of results.

Analyzed matrices

Luteolin quantification is applicable to a wide range of plant matrices and formulated products:

• Extracts of medicinal plants (artichoke, thyme, rosemary, chamomile, etc.)
• Vegetable powders and raw materials
• Flavonoid-based food supplements
• Infusions, herbal teas, decoctions
• Cosmetic products containing antioxidant extracts

This analysis is essential in the development of products with anti-aging, anti-inflammatory or nervous system protective effects.

Industrial applications and purposes

Luteolin testing is particularly useful for:

• Standardize plant extracts according to defined quality criteria (mg/g or mg/mL)
• Monitor regulatory compliance (particularly with regard to health claim statements)
• Optimizing cosmetic formulations or antioxidant supplements
• Carry out comparative studies on flavone contents between different botanical sources
• Evaluate the impact of extraction or drying processes on active ingredient content

It is also a traceability criterion to differentiate plant origins or manufacturing batches.

Additional analyses available at YesWeLab

To go further in the evaluation of flavones and polyphenols, we propose:

• Determination of luteolin-7-O-glucoside – its glycosylated form common in chamomile and artichoke
• Assay of luteolin-7-glucuronide – a metabolite useful in pharmacokinetics and bioavailability
• Dosage of apigenin – a flavone similar to luteolin, with anti-inflammatory properties
• Determination of total flavonoids – global method for complex extracts

Why choose YesWeLab for luteolin testing?

At YesWeLab , we facilitate access to high-quality analyses thanks to a network of more than 200 partner laboratories, rigorously selected for their analytical expertise. We offer:

• Personalized scientific support
• Controlled deadlines, adapted to your development or quality control needs
• A centralized, intuitive and secure digital analysis management platform
• Compliance with the most demanding analytical standards (ISO 17025, COFRAC)

Need a luteolin dosage in your extracts?

Contact our team for a personalized quote or to discuss your analysis project. Our experts will help you define the method best suited to your matrix and objectives.