Uncarin E dosage

Uncarine E is an oxindolic alkaloid isolated from Uncaria tomentosa , also known as cat's claw. This plant, native to South America, has long been used in traditional medicine for its immunomodulatory and anti-inflammatory properties. In the nutraceutical field, uncarine E is being studied as a molecule of interest for its potential effects on modulating the immune system and protecting against certain oxidative processes.

The dosage of uncarin E is essential to guarantee the quality and standardization of cat's claw plant extracts. It ensures product traceability, validates their conformity to specifications, and meets consumer expectations in terms of safety and efficacy.

Analytical methods:
The determination of uncarin E relies primarily on liquid chromatography:

• HPLC with UV or DAD detection, used for routine controls on dry extracts or powders.
• LC-MS or LC-MS/MS, allowing very specific quantification, with a detection limit adapted to complex matrices such as multicomponent food supplements.

These methods offer excellent reproducibility and comply with international standards applied to the nutraceutical industry.

Matrices involved:
Uncarin E can be measured in different matrices:

• Dry extracts of Uncaria tomentosa
• Powders of ground plants
• Dietary supplements in capsule or tablet form
• Nutraceutical blends incorporating cat's claw

Industrial applications

• Standardization of cat's claw extracts to guarantee a constant content of oxindolic alkaloids.
• Development of dietary supplements with immune or anti-inflammatory properties.
• Validation of the quality of imported plant-based raw materials.
• Research and development of new functional products based on Uncaria tomentosa .

Further analyses:
The measurement of uncarine E can be combined with other analyses of alkaloids and bioactive markers to provide a more complete picture of plant extracts:

• Rhynchophylline dosage
• Total polyphenol content

These additional services make it possible to evaluate the synergy between the compounds and to obtain a complete characterization of the extract.

Regulations and Quality Challenges:
In the nutraceutical sector, compliance and traceability of cat's claw-based products are essential. The measurement of uncarin E contributes to the standardization of extracts and meets market expectations for transparency and safety. Manufacturers can thus enhance the value of their formulations and guarantee reliable products that comply with European and international regulatory requirements.

YesWeLab's expertise:
YesWeLab works with a network of accredited and certified partner laboratories (ISO 17025, COFRAC, etc.), selected based on the matrix and analytical needs. Our scientific team supports you at every stage, from defining your analytical requirements to delivering the results, guaranteeing responsiveness and accuracy.

Thanks to our digital platform, you benefit from simplified management of your analyses: sample submission, real-time tracking, and centralized receipt of results. Since 2020, numerous manufacturers, distributors, and engineering firms have trusted us to manage their analyses.