Uncarine E dosage

Uncarine E is an oxindole alkaloid isolated from Uncaria tomentosa , also known as cat's claw. This plant, native to South America, has long been used in traditional medicines for its immunomodulatory and anti-inflammatory properties. In the nutraceutical field, uncarine E is being studied as a molecule of interest for its potential effects on the modulation of the immune system and protection against certain oxidative processes.

Uncarin E assay is essential to ensure the quality and standardization of cat's claw plant extracts. It helps ensure product traceability, validate their compliance with specifications, and meet consumer expectations for safety and efficacy.

Analytical methods
The dosage of uncarine E is mainly based on liquid chromatography:

• HPLC with UV or DAD detection, used for routine checks on dry extracts or powders.
• LC-MS or LC-MS/MS, allowing very specific quantification, with a detection limit adapted to complex matrices such as multi-component food supplements.

These methods offer excellent reproducibility and comply with international standards applied to the nutraceutical industry.

Matrices involved
Uncarine E can be measured in different matrices:

• Dry extracts of Uncaria tomentosa
• Ground plant powders
• Food supplements in the form of capsules or tablets
• Nutraceutical blends incorporating cat's claw

Industrial applications

• Standardization of cat's claw extracts to ensure consistent oxindole alkaloid content.
• Development of food supplements for immune or anti-inflammatory purposes.
• Validation of the quality of imported plant raw materials.
• Research and development of new functional products based on Uncaria tomentosa .

Additional analyses
The dosage of uncarine E can be combined with other analyses of alkaloids and bioactive markers, in order to offer a more complete view of plant extracts:

• Rhynchophylline dosage
• Determination of total polyphenols

These complementary services make it possible to evaluate the synergy between the compounds and to obtain a complete characterization of the extract.

Regulations and quality issues
In the nutraceutical sector, compliance and traceability of cat's claw products are essential. The dosage of uncarin E contributes to the standardization of extracts and meets market expectations in terms of transparency and safety. Manufacturers can thus enhance the value of their formulations and guarantee reliable products that comply with European and international regulatory requirements.

YesWeLab Expertise
YesWeLab works with a network of accredited and certified partner laboratories (ISO 17025, COFRAC, etc.), selected based on the matrix and analytical needs. Our scientific team supports you every step of the way, from defining your analytical needs to delivering results, ensuring responsiveness and accuracy.

Thanks to our digital platform, you benefit from simplified management of your analyses: sample submission, real-time tracking, and centralized receipt of results. Since 2020, numerous manufacturers, distributors, and design offices have trusted us to manage their analyses.