Leonurine assay

Leonurine is an isoquinoline alkaloid primarily extracted from plants of the genus Leonurus , such as Leonurus japonicus and Leonurus cardiaca . These species are traditionally used in Asian and European medicine for their beneficial effects on cardiovascular health, hormonal regulation, and general well-being.

In the nutraceutical and phytotherapeutic industries, leonurine is studied for its antioxidant, anti-inflammatory, and cardiovascular-protective properties. It is found in dietary supplements, dry extracts, and dermocosmetic formulations designed to enhance its protective and regulatory effects.

Importance of leonurine measurement

Measuring leonurine levels is an essential step for:

• Standardize plant extracts and guarantee a precise content of active ingredient.
• Validate the quality of raw materials derived from medicinal plants.
• To monitor the regulatory compliance of nutraceutical and cosmetic products.
• Ensuring the stability and traceability of formulations throughout their life cycle.

In a rapidly growing market, controlling the content of alkaloids such as leonurine is a key factor in differentiation and safety for manufacturers.

Analytical methods

The analysis of leonurine is based primarily on high-performance liquid chromatography (HPLC) and liquid chromatography coupled with mass spectrometry (LC-MS).

• HPLC-DAD allows reliable quantification by UV detection, ideal for simple extracts.
• LC-MS/MS ensures high sensitivity and specificity, even in complex matrices such as multi-component food supplements.
• These approaches can be complemented by UPLC for fast and accurate separations.

YesWeLab relies on a network of specialized laboratories capable of carrying out high-precision analyses, in accordance with current standards (ISO 17025, COFRAC).

Matrices analyzed

Leonurine assay can be applied to a wide range of matrices:

• Standardized plant extracts of Leonurus spp.
• Dietary supplements in the form of capsules, powders or tablets.
• Liquid preparations for phytotherapeutic purposes.
• Cosmetic formulations containing plant-based active ingredients.

This versatility allows it to address the needs of both R&D laboratories and manufacturers seeking to secure their production.

Industrial applications

The analytical control of leonurine is relevant to many sectors:

• Nutraceuticals: development of food supplements based on standardized extracts.
• Phytotherapy: validation of the composition of products derived from traditional medicine.
• Functional cosmetics: integration of natural active ingredients into creams or lotions with protective and antioxidant properties.
• Research and innovation: identification of biomarkers and clinical studies on the biological effects of the molecule.

Related analyses and internal linking

YesWeLab also offers the measurement of other plant-based bioactive molecules complementary to leonurine, allowing manufacturers to strengthen the traceability of their formulations:

• Convallatoxin assay for the control of cardiac glycosides.
• Corynanthine assay for the standardization of indole alkaloids.
• Costunolide dosage in medicinal plant extracts.
• Assay of emetine for the control of isoquinoline alkaloids.
• Determination of enoxolone in licorice products.

This network of analyses makes it possible to offer a complete solution for characterizing active ingredients of plant origin.

YesWeLab support

Since 2020, YesWeLab has been supporting manufacturers, distributors, and engineering firms with their analytical needs through an intuitive digital platform. Our role is to select the most suitable laboratory for you based on the matrix, method, and certification required.

Most of our partner laboratories are ISO 17025 certified and COFRAC accredited, guaranteeing reliable and recognized results. For specific requirements, our scientific team designs customized protocols to precisely meet your needs.