Helveticoside assay

Helveticoside analysis is essential for manufacturers of cosmetics, nutraceuticals, and functional foods. This phenolic glycoside, naturally present in certain plants, is valued for its soothing, antioxidant, and revitalizing properties. Quantifying it allows for the standardization of botanical extracts, ensures their efficacy, and guarantees that finished products comply with health or cosmetic claims.

Understanding helveticoside and its applications

Helveticoside is a bioactive compound derived from glycosylated phenolic structures. It is found primarily in certain plant extracts used in:

• Cosmetics : formulations for skin care, soothing products, antioxidant serums and calming lotions.
• Nutraceutical : dietary supplements that exploit its revitalizing and protective potential against oxidative stress.
• Phytotherapy : integration into traditional or innovative preparations targeting balance and well-being.

Its presence in an extract is often associated with added value, strengthening the credibility and differentiation of products in a highly competitive market.

Analytical methods for the determination of helveticoside

Helveticoside analysis relies on liquid chromatography techniques, recognized for their reliability and sensitivity:

• HPLC (high-performance liquid chromatography) : a classic method for precisely separating and quantifying helveticoside in plant extracts or complex formulations.
• UPLC (ultra performance liquid chromatography) : a faster and more efficient version of HPLC, suitable for large-scale batch control.
• LC-MS or LC-MS/MS (liquid chromatography coupled with mass spectrometry) : offers specific identification and high sensitivity, essential for detecting helveticoside even at low concentrations.

These approaches can be coupled with UV or MS detection, depending on the type of matrix and analytical needs, in order to obtain robust and reliable quantification.

Sectors affected by helveticoside analysis

Helveticoside measurement is particularly relevant in several sectors:

• Cosmetics : quality control of skin care and soothing formulations, guaranteeing the presence of valuable plant-based active ingredients.
• Human nutrition : validation of functional products enriched with botanical extracts.
• Nutraceuticals : standardization of food supplements targeting oxidative stress and general well-being.
• Plants and phytotherapy : characterization of phytocomplexes and plant extracts for research and marketing.

Typically analyzed matrices

Helveticoside analysis is performed in a wide variety of matrices, including:

• Standardized plant extracts
• Cosmetic creams, lotions and serums
• Plant powders or nutraceutical capsules
• Beverages or foods enriched with botanical extracts
• Phytotherapy preparations

Each type of matrix requires a suitable analytical approach to ensure the accuracy of the results.

Quality and compliance issues

In a rapidly expanding market, control of helveticoside addresses several strategic issues:

• Standardization : ensuring a homogeneous concentration of helveticoside between different production batches.
• Safety : control the quality of the extracts to avoid any uncontrolled variability.
• Regulations : comply with the standards in force in the cosmetics, food and nutraceutical sectors.
• Marketing value : highlighting the presence of measured and certified natural assets to strengthen consumer confidence.

YesWeLab support for your helveticoside analyses

YesWeLab relies on a network of partner laboratories specializing in chromatographic and physicochemical analyses. Our accredited and certified partners (ISO 17025, COFRAC) apply validated methods to guarantee reliable results recognized by authorities and market players.

Our digital platform allows you to manage your analyses with ease:

• Online submission of your samples
• Real-time tracking of your requests
• Fast and secure delivery of results

Our scientific team will assist you in choosing the methods best suited to your matrices and specific needs, in order to optimize your analytical projects.

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• Assay of withanolides and withanosides