Dosage of g-strophanthin

G-strophanthin, also known as ouabain, is a cardiac glycoside extracted mainly from Strophanthus gratus . It belongs to the class of cardiac glycosides, traditionally used for their action on myocardial function. Although its therapeutic use is now strictly regulated, it remains analyzed in nutraceutical, ethnobotanical or regulatory contexts for:

• Secure plant extracts containing active heterosides,
• Avoid any contamination or excessive dosage,
• Standardize plant preparations,
• Meet traceability and compliance requirements.

Why measure g-strophanthin?

The dosage of g-strophanthin is essential for assessing the concentration of an active ingredient with high pharmacological activity. Present naturally in certain plants, its potential toxicity justifies rigorous analytical control. This analysis allows:

• To validate the conformity of botanical extracts intended for nutraceutical or cosmetic use,
• To prevent the risks of adverse effects from overdose,
• To ensure regulatory transparency, particularly in the export of raw materials.

Analytical methods used

The dosage is carried out according to the most reliable analytical standards:

HPLC (High Performance Liquid Chromatography)

High-performance liquid chromatography with UV or DAD detection allows for accurate quantification in single extracts or tinctures.

LC-MS or LC-MS/MS

Liquid chromatography-mass spectrometry (LC-MS/MS) is preferred for complex matrices or low concentrations, ensuring optimal specificity and sensitivity.

Affected matrices

• Standardized plant extracts for tonic or cardiotonic purposes,
• Mother tinctures and galenic preparations from Strophanthus gratus ,
• Herbal food supplements containing glycosides,
• Ethnobotanical products or traditional preparations.

Industrial sectors concerned

• Nutraceuticals and phytotherapy: verification of active ingredient levels in medicinal plants;
• Scientific and clinical research: studies on the physiological effects of g-strophanthin;
• Plant extract industry: quality control and standardization of raw materials;
• Regulatory control and safety: compliance with set thresholds or exclusion of prohibited active substances.

Recommended related analyses (internal links)

To complete your analyses around cardioactive plant extracts, you can also consult:

• Colchicine dosage – toxic mitotic-type alkaloid to be monitored in extracts;
• Dosage of galegine – alkaloid with hypoglycemic effect from Galega officinalis ;
• Total polyphenols assay – monitoring of overall antioxidant activity;
• Dosage of diosmetin – methylated flavone with vasoprotective effect.

YesWeLab analytical expertise

At YesWeLab, we select specialized partner laboratories, ISO 17025 certified and/or COFRAC accredited, capable of meeting the specific requirements related to the analysis of natural glycosides.

With our digital platform, you benefit from:

• Quick access to quotes,
• Personalized scientific support,
• Traceability of samples and results,
• Validated methods for all types of matrices.

Since 2020, we have been supporting manufacturers, formulators, R&D laboratories and distributors in the secure management of their analyses.

Order your dosage of g-strophanthin

Need to measure g-strophanthin in your plant extracts or herbal products? Our team will guide you through:

• The choice of the appropriate analytical method (HPLC, LC-MS);
• Establishing a tailor-made dosage protocol;
• Fast and reliable analysis of your samples.