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Furanochromone dosage (in the form of cimifugin)

Furanochromone dosage (in the form of cimifugin)

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

37921-38-3

Description

Cimicifugin is a furanochromone naturally present in Cimicifuga racemosa, also known as black cohosh. Long used in herbal medicine, this molecule is primarily sought after for its potential effects on women's health, particularly during menopause. It is one of the key analytical markers used to ensure the quality and traceability of Cimicifuga extracts.

Why measure cimifugine?

Furanochromone (cimifugin) level testing is essential for:

  • Standardize the extracts of Cimicifuga racemosa used in nutraceuticals or phytotherapy,
  • Check the active ingredient content in dietary supplements designed for hormonal regulation
  • Ensuring regulatory compliance of marketed plant-based products,
  • Validate functional claims related to feminine comfort.

The presence and concentration of cimifugin in the extracts ensure reproducible efficacy, while controlling the risks associated with natural variability.

Analytical methods: precision and reliability

The dosage of cimifugin is based on reference methods recognized in the field of plant protection product analysis:

HPLC (High Performance Liquid Chromatography)

Used for precise quantification in plant matrices, this method relies on chromatographic separation followed by UV or DAD detection.

LC-MS / LC-MS-MS (Liquid Chromatography coupled with mass spectrometry)

Recommended for complex matrices or low concentrations, this method allows for specific identification and high-sensitivity detection.

Matrices involved in the cimifugin assay

  • Standardized dry extracts of Cimicifuga racemosa,
  • Plant powders or capsules containing botanical extracts,
  • Dietary supplements for hormonal or feminine well-being purposes,
  • Phytotherapeutic products formulated with black cohosh.

Areas of application

  • Nutraceuticals: formulation and quality control of supplements for menopause;
  • Medicinal plants: evaluation of the active ingredients present in the extracts;
  • Natural extracts industry: standardization of raw materials;
  • Clinical or toxicological research: studies on the efficacy or safety of use.

Further analyses recommended (internal links)

You can enhance the quality control of your plant extracts with:

YesWeLab: analytical expertise dedicated to plant extracts

At YesWeLab, we provide you with a network of partner laboratories certified to ISO 17025 and/or accredited by COFRAC, experts in phytocompound analysis.

Thanks to our intuitive digital platform, you benefit from:

  • With quick access to online quotes,
  • Personalized scientific support from our team,
  • Complete traceability of your samples,
  • From a choice of methods adapted to your matrices and analytical objectives.

Since 2020, hundreds of manufacturers, R&D laboratories and formulators have trusted us for the outsourced management of their analytical needs.

Order your cimifugin dosage online

Do you want to analyze the furanochromone (cimifugin) content of your Cimicifuga racemosa extracts or phytotherapeutic products? We can assist you with:

  • The choice of method (HPLC or LC-MS),
  • Implementing an analytical strategy tailored to your product,
  • Processing and delivering results within the required timeframe.

Other analyses we perform

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