Fructosamine Dosage

Fructosamine CAS 3446-28-0) is a non-enzymatic glycation product formed by the reaction of glucose with circulating proteins, mainly albumin. It is a reliable indicator of average blood glucose levels over the last two to three weeks, unlike blood glucose, which reflects the instantaneous metabolic state.
In the field of animal health , fructosamine measurement is a method of choice for assessing glycemic control , detecting chronic hyperglycemia , or monitoring the effectiveness of hypoglycemic treatment.
This analysis is also useful for assessing glycation reactions in fortified products or nutritional formulations for pets and livestock.

Analytical methods used

Fructosamine analysis is based on two main approaches:

• Spectrophotometric (colorimetric) method : based on the reduction of nitroblue tetrazolium (NBT) to a colored compound proportional to the concentration of fructosamine. This method is rapid, reliable and suitable for routine analyses on animal sera.
• Enzyme-linked immunosorbent assay (ELISA) : Used for specific quantification in complex matrices or for research applications.

reproducible and comparable results , meeting international analytical standards.
For enriched products or nutritional formulations, the spectrophotometric method can be coupled with UV-Vis spectrophotometry to improve measurement accuracy.

Affected matrices

Fructosamine dosage applies to several types of matrices from the veterinary or nutritional field:

• Animal sera (dog, cat, horse, bovine, etc.) for metabolic monitoring.
• Enriched products or food supplements intended for animals.
• Nutritional raw materials used in the formulation of functional foods.

This analysis helps to guarantee the stability of formulations , to monitor the metabolic effects of certain ingredients and to validate the conformity of animal health products.

Applications and usefulness of dosage in animal health

The dosage of fructosamine is of particular interest to veterinarians, nutritionists and manufacturers of supplements intended for animal health:

• Evaluation of glycemic control in diabetic animals.
• Therapeutic monitoring of treatments aimed at regulating blood sugar.
• Quality control of products intended to support energy metabolism or metabolic health.
• Research and innovation : studies on protein glycation and its impact on cellular and oxidative health.

This analysis can be combined with other metabolic biomarkers such as glucose assay , total cholesterol assay or triglyceride assay for a complete assessment of the animal biochemical profile.

Importance for quality control and research

Fructosamine levels reflect the average glucose concentration over a given period, making it an essential marker for:

• Monitoring the development of diabetes mellitus in domestic animals.
• Determine the effectiveness of a diet or nutritional treatment.
• Identify latent metabolic disorders related to diet or age.

In the context of the formulation of functional foods or nutraceutical supplements, this analysis contributes to the validation of the announced metabolic effects and to the traceability of the products .

YesWeLab expertise

YesWeLab provides its network of partner laboratories , ISO 17025 and COFRAC accredited, specialized in biochemical and metabolic analyses for animal health .
Each request is handled in a personalized manner, taking into account the biological matrices , analytical objectives and regulatory requirements of the client.
Our experts support manufacturers, veterinary clinics and R&D laboratories in the choice of methods, the interpretation of results and the implementation of regular metabolic monitoring.

Thanks to the YesWeLab digital platform , you can centralize the management of your analyses: request for quotes, sample tracking, receipt of technical reports and data archiving.

For any specific request, contact our scientific team now to benefit from complete support in your biochemical and nutritional analyses.