Fraxin (coumarin) dosage

Fraxin is a heteroside of the coumarin family, mainly found in the bark and leaves of the ash tree (Fraxinus excelsior and related species). This natural molecule is studied in the field of phytotherapy where it serves as a quality marker for standardized plant extracts. Its laboratory dosage is essential to ensure the compliance, safety and efficacy of plant-based products intended for the nutraceutical and pharmaceutical sectors.

Fraxin is identified by the CAS number 524-30-1 and is distinguished by its biological properties, notably its role in the antioxidant and protective activity of ash extracts. Controlling its content in plant preparations is therefore essential to ensure a homogeneous formulation that complies with regulatory requirements.

Analytical methods for the determination of fraxin

The dosage of fraxin is based on chromatographic techniques, allowing precise and reliable quantification even in complex matrices such as plant extracts.

High-performance liquid chromatography (HPLC) is the gold standard for the separation and quantification of coumarins. It provides excellent resolution and reproducible measurement of fraxin, even at low concentrations.

Liquid chromatography-mass spectrometry (LC-MS) is a recommended complementary method to confirm the molecular identity of fraxin and simultaneously detect other bioactive compounds. These analytical techniques guarantee selective detection and precision adapted to industrial requirements, particularly for extract standardization and compliance with specifications.

Affected matrices

The dosage of fraxin applies to different matrices from medicinal plants and food supplements, such as:

• • standardized plant extracts
  • ash leaf infusions
  • plant powders used in nutraceuticals
  • complex preparations integrating several natural active ingredients

The determination of fraxin is recommended as part of the quality control of raw materials and finished products, in order to ensure consistency and conformity.

Importance of dosage for manufacturers

In the nutraceutical, herbal medicine, and nutrition sectors, extract standardization is a key step in ensuring product efficacy and safety. The presence and concentration of fraxin serve as quality criteria, allowing manufacturers and distributors to ensure regulatory compliance, control the natural variability of raw materials, scientifically promote their products, and ensure traceability for consumers.

The dosage of fraxin is therefore part of a global approach to quality control and responsible marketing of natural health products.

Additional analyses available

In addition to fraxin, other bioactive compounds from the coumarin and flavonoid family can be analyzed for a complete characterization of plant extracts. YesWeLab offers in particular:

Esculin (coumarin) dosage
Rutin (flavonoid)
dosage Quercetin (flavonoid) dosage
Hyperoside (flavonoid) dosage

These services make it possible to obtain a complete analytical profile of plant extracts, reinforcing the standardization and differentiation of products on the market.

YesWeLab expertise

YesWeLab relies on a carefully selected network of partner laboratories, the majority of which are ISO 17025 and COFRAC certified and accredited. Each analysis is entrusted to the most suitable laboratory based on the matrix to be tested, the required method, and each client's regulatory constraints.

Since 2020, the YesWeLab digital platform has enabled manufacturers, distributors and design offices to centralize their analytical needs, simplify sample management and receive reliable results as quickly as possible.

The scientific team supports each project with precision and responsiveness, in order to meet the specific requirements of each specification.