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Fibronectin assay

Fibronectin assay

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

86088-83-7

Description

Fibronectin is a glycoprotein found in the extracellular matrix and plasma, playing a fundamental role in cell adhesion, wound healing, and tissue repair. It is involved in numerous biological processes, including skin regeneration, blood coagulation, and modulation of cell-matrix protein interactions.

Its laboratory measurement is an essential tool in both the biomedical field and the cosmetic and dermocosmetic industries. Quantifying fibronectin makes it possible to evaluate the effectiveness of formulations, monitor biological biomarkers, and ensure the quality of functional skin products.

Importance of dosage

Fibronectin dosage addresses several industrial and scientific challenges.

• In animal health and biomedical research, it is used to assess healing, inflammation and certain pathological processes.
• In the cosmetics and dermocosmetics sector, it is used to monitor the effectiveness of formulations intended for skin regeneration, wound care and protection of the epidermal barrier.
• For manufacturers, it is a quality and conformity criterion, allowing formulations to be standardized and the reproducibility of results to be guaranteed.

Controlling fibronectin content is therefore essential to scientifically support product performance and strengthen their positioning on the market.

Analytical method used

Fibronectin measurement is mainly based on the ELISA (Enzyme-Linked Immunosorbent Assay) technique, a sensitive and specific immunological method.

• This approach is based on the recognition of fibronectin by specific antibodies, allowing selective detection even at low concentrations.
• ELISA offers high reproducibility and excellent precision, suitable for complex biological and cosmetic matrices.
• It is widely used in research laboratories, in quality control and in the development of innovative products.

Thanks to its sensitivity and robustness, this method constitutes the reference for the reliable quantification of fibronectin.

Affected matrices

Fibronectin assay is applicable to different types of matrices, including:

• animal sera for animal health studies or basic research
• biological extracts intended for the evaluation of biomarkers
• dermocosmetic formulations and functional skin care

This diversity of matrices makes it possible to address the needs of research laboratories, animal health manufacturers and cosmetic product manufacturers.

Industrial and scientific applications

Fibronectin analysis is of interest to several sectors:

• in cosmetics, it allows the regenerative and healing efficacy of topical formulations to be verified
• in research, it constitutes a biomarker of cellular adhesion, inflammatory processes and healing
• in animal health, it contributes to the study of biological mechanisms of repair and immune response

This analysis is part of a process of quality control, product development and scientific innovation.

Additional analyses available

YesWeLab also offers associated analyses that can enrich the evaluation of biological formulations and extracts:

Collagen dosage
Elastin dosage
Hyaluronic acid dosage

These additional services make it possible to characterize the extracellular matrix more broadly and to evaluate the overall effectiveness of cosmetic and biomedical products.

YesWeLab expertise

YesWeLab collaborates with a network of partner laboratories specialized in biological and cosmetic analyses, rigorously selected and for the most part ISO 17025 certified and COFRAC accredited.

Since 2020, our digital platform has simplified the management of analytical needs for manufacturers, distributors, and design offices. It centralizes requests, enables sample tracking, and guarantees reliable and fast results.

Our scientific team supports each project by providing solutions adapted to the matrices and specific requirements of each client.

Other analyses we perform

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