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Fibronectin assay

Fibronectin assay

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

86088-83-7

Description

Fibronectin is a glycoprotein found in the extracellular matrix and plasma, playing a fundamental role in cell adhesion, wound healing, and tissue repair. It is involved in numerous biological processes, including skin regeneration, blood coagulation, and the modulation of interactions between cells and matrix proteins.

Its laboratory measurement is an essential tool in both the biomedical field and the cosmetic and dermocosmetic industries. Quantifying fibronectin allows for the evaluation of formulation efficacy, the monitoring of biological biomarkers, and the assurance of the quality of functional skin products.

Importance of dosage

Fibronectin assay addresses several industrial and scientific challenges.

• In animal health and biomedical research, it is used to assess wound healing, inflammation, and certain pathological processes.
• In the cosmetics and dermocosmetics sector, it allows for monitoring the efficacy of formulations intended for skin regeneration, wound care, and protection of the epidermal barrier.
• For manufacturers, it constitutes a criterion of quality and conformity, enabling the standardization of formulations and guaranteeing the reproducibility of results.

Controlling fibronectin content is therefore essential to scientifically support product performance and strengthen their market positioning.

Analytical method used

Fibronectin assay is mainly based on the ELISA (Enzyme-Linked Immunosorbent Assay) technique, a sensitive and specific immunological method.

• This approach relies on the recognition of fibronectin by specific antibodies, enabling selective detection even at low concentrations.
• ELISA offers high reproducibility and excellent precision, making it suitable for complex biological and cosmetic matrices.
• It is widely used in research laboratories, quality control, and the development of innovative products.

Thanks to its sensitivity and robustness, this method constitutes the reference for the reliable quantification of fibronectin.

Affected matrices

Fibronectin assays are applicable to various types of matrices, including:

• Animal sera for animal health studies or basic research
• Biological extracts for biomarker evaluation
• Dermocosmetic formulations and functional skincare

This diversity of matrices makes it possible to address the needs of research laboratories, animal health manufacturers and cosmetic product manufacturers.

Industrial and scientific applications

Fibronectin analysis is of interest to several sectors:

• In cosmetics, it allows verification of the regenerative and healing efficacy of topical formulations.
• In research, it constitutes a biomarker of cell adhesion, inflammatory processes, and wound healing.
• In animal health, it contributes to the study of the biological mechanisms of repair and immune response.

This analysis is part of a quality control, product development and scientific innovation approach.

Additional analyses available

YesWeLab also offers related analyses that can enhance the evaluation of formulations and biological extracts:

Collagen dosage
, elastin dosage,
hyaluronic acid dosage

These additional services allow for a broader characterization of the extracellular matrix and for evaluating the overall effectiveness of cosmetic and biomedical products.

YesWeLab expertise

YesWeLab collaborates with a network of partner laboratories specializing in biological and cosmetic analyses, rigorously selected and mostly ISO 17025 certified and COFRAC accredited.

Since 2020, our digital platform has simplified the management of analytical needs for manufacturers, distributors, and engineering firms. It centralizes requests, enables sample tracking, and guarantees reliable and rapid results.

Our scientific team supports each project by providing solutions tailored to the matrices and specific requirements of each client.

Other analyses we perform

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