Estradiol dosage

Estradiol is a steroid hormone belonging to the estrogen family. Although it is primarily associated with animal and human physiology, it is sometimes found in trace amounts in certain plants or natural substances. Its presence may be linked to potential hormonal effects, which justifies its analytical monitoring in various contexts. In the nutraceutical and phytotherapeutic industry, estradiol measurement is particularly relevant to ensure the safe use of plant extracts and to assess possible endocrine effects.

Analytical techniques used
Estradiol measurement requires very high sensitivity because it is often present at very low concentrations. The analysis is carried out by high-performance liquid chromatography (HPLC) coupled with mass spectrometry (LC-MS or LC-MS/MS). This approach guarantees:

• high specificity to differentiate estradiol from other estrogens or metabolites,
• precise quantification even in complex matrices,
• reliable detection at trace levels.

The use of LC-MS/MS also allows the elimination of interferences from other natural compounds and the obtaining of a complete analytical profile.

Industrial and regulatory applications
Estradiol measurement applies to several sectors:

• Nutraceuticals : quality control of food supplements and herbal preparations.
• Phytotherapy : evaluation of the safety of plant extracts used for their functional effects.
• Cosmetics : verification of the absence or presence of trace amounts of hormones in natural formulations.
• Natural products of animal origin : monitoring of hormonal levels in certain raw materials.

From a regulatory perspective, the determination of estradiol may be required as part of compliance and health safety studies, in particular to guarantee the absence of undesirable hormonal effects.

Analyzed matrices
The analyses are carried out on different types of samples:

• plant extracts (medicinal plants, natural preparations),
• powders and food supplements,
• complex natural products,
• non-medical animal substances.

Scientific interest and quality control
The quantification of estradiol is of major interest for scientific research and the development of innovative products. It allows in particular:

• to better understand the interactions between phytohormones and metabolites,
• to assess the stability and purity of natural extracts,
• to anticipate possible regulatory issues related to endocrine effects.

By integrating this type of analysis into their quality control strategy, manufacturers are strengthening the safety of their products and meeting growing consumer expectations in terms of transparency and traceability.

YesWeLab, your analytical partner
At YesWeLab, we collaborate with a carefully selected network of accredited and certified partner laboratories (ISO 17025, COFRAC, etc.) to guarantee reliable results that comply with international standards. Our experts assist nutraceutical, plant, and natural product professionals in choosing the analytical methods best suited to their needs.

Our digital platform allows you to centralize your requests, track your samples and receive your results as quickly as possible.

Additional analyses
Estradiol dosage can be combined with other analyses of bioactive molecules for overall monitoring of plant extracts:

• Flavonoid dosage

These additional analyses strengthen quality control and allow better characterization of natural matrices.

Entrust your analyses to YesWeLab
Since 2020, numerous manufacturers, distributors, and design offices have trusted YesWeLab to manage their analyses. Our scientific team is committed to meeting your specific needs with precision, responsiveness, and transparency.

To learn more or submit a specific need regarding estradiol dosage, contact our team now and get a personalized quote.