Ellagic acid dosage

Ellagic acid is a natural polyphenol derived from the degradation of ellagitannins, widely found in plants such as pomegranate, raspberry, strawberry, blackberry, and oak bark. It is recognized for its powerful antioxidant properties, its protective role against skin cells exposed to UV radiation (photoprotective effect), and its potential antiproliferative effects, which have been studied in nutraceutical and cosmetic research.

The dosage of ellagic acid is therefore essential for qualifying and promoting plant extracts used in health-related food supplements, anti-aging cosmetics, or protective skincare products. It allows for the standardization of polyphenol-rich formulations, the control of active content, and the demonstration of an ingredient's quality from a functional and regulatory perspective.

Analytical methods used

The analysis of ellagic acid is based on high-performance chromatography techniques coupled with suitable detectors:

• HPLC-DAD (UV-visible detection): method commonly used for high concentration extracts or for comparative assays,
• LC-MS/MS: essential for trace detection or for complex matrices,
• Specific colorimetric methods: sometimes used for rapid control or for semi-quantitative applications.

These methods ensure high accuracy in the identification and quantification of ellagic acid, even in highly pigmented matrices or those rich in other polyphenols.

Affected matrices

Ellagic acid assay is relevant for many plant-derived matrices, including:

• Extracts of pomegranate, strawberry, raspberry, blackberry
• Bark and wood of oak or other hardwoods rich in tannins
• Antioxidant or anti-aging food supplements
• Cosmetic products (serums, lotions, creams)
• Functional foods or fortified drinks
• The analysis can be part of a quality control, product development or regulatory verification process, particularly for the claim of antioxidant properties or naturalness.

Additional analyses available at YesWeLab

For a complete characterization of plant extracts for health or beauty purposes, YesWeLab offers several relevant complementary analyses related to ellagic acid:

1. Punicalagin dosage : the main ellagitannin in pomegranate, a direct precursor of ellagic acid in the body.
2. Determination of total flavonoids (or specific ones such as quercetin, kaempferol or rutin) – to assess the polyphenolic synergy of the extracts.
3. Overall antioxidant capacity (ORAC or DPPH methods) – to measure the functional effectiveness of polyphenol-rich extracts.

These analyses make it possible to demonstrate the nutritional, functional or cosmetic value of plant raw materials, and to establish a complete analytical profile for buyers, formulators or regulatory authorities.

Why choose YesWeLab for your analyses?

At YesWeLab, we carefully select the laboratories best suited to your needs, taking into account:

• Types of matrices to be analyzed (liquids, dry extracts, cosmetics, foods),
• Required analytical techniques (HPLC, LC-MS/MS, UV),
• And required certifications (ISO 17025, COFRAC, BPL, etc.).

Since 2020, we have been supporting manufacturers, nutraceutical brands, R&D laboratories and formulators in their analytical needs, via a simple and responsive digital platform to centralize the management of samples, quotes and results.

Need to measure ellagic acid or other polyphenols in your products? Contact our scientific team now and get a personalized quote as soon as possible.