Valerenic acid dosage

Valerenic acids are bioactive compounds found in the roots of Valeriana officinalis , a medicinal plant known for its relaxing and sedative properties. These molecules play a key role in the effectiveness of valerian extracts used in herbal medicine and in the formulation of dietary supplements for well-being and stress management. Quantification of valerenic acids is essential to ensure the standardization, safety, and traceability of finished products. It allows manufacturers to guarantee the compliance of their formulations with regulatory requirements and consumer expectations.

Analytical methods for the determination of valerenic acids

The determination of valerenic acids is based on high-precision chromatographic techniques, allowing reliable and reproducible results to be obtained.

• HPLC-UV (High Performance Liquid Chromatography with UV detection) : reference method for the quantification of these compounds in various extracts and finished products.
• LC-MS/MS (Liquid Chromatography coupled with Tandem Mass Spectrometry) : advanced technique offering increased sensitivity, particularly suited to complex matrices or multi-component formulations.

These methods are part of a broader framework of quality control applied to medicinal plants, like HPLC and MS/MS, which are widely used for the identification and quantification of active plant substances.

Applications and challenges for the nutraceutical industry

The analysis of valerenic acids is aimed at several players in the nutraceutical and phytotherapeutic sector:

• Food supplement manufacturers: to ensure the standardization of valerian extracts.
• R&D laboratories: to study the efficacy and composition of valerian-based formulations.
• Distributors and importers of plant raw materials: to ensure the quality and conformity of batches.

This approach is part of a broader logic of promoting plant-based active ingredients, in the same way as the dosage of compounds such as theanine , theobromine or trigonelline , also offered by YesWeLab.

Matrices affected by the analysis

Valerenic acid assays can be performed on a wide variety of valerian-derived matrices: infusions and herbal teas, dry and hydroalcoholic extracts, root powders, finished products in the form of capsules, tablets, or complex mixtures. The chosen methodology is adapted according to the nature of the matrix and the specific needs of the customer, whether for routine quality control, regulatory validation, or production monitoring.

Importance of standardization and traceability

The standardization of valerian extracts not only guarantees the therapeutic efficacy of the products, but also consumer safety. The dosage of valerenic acids makes it possible to verify the actual content of active ingredients claimed on the labeling, to control consistency between different production batches and to meet regulatory requirements for the marketing of nutraceutical products. These challenges are similar to those encountered for other plant molecules such as tyramine , tryptamine or gymnemic acids , the dosage of which also contributes to securing the formulations.

YesWeLab expertise for your valerian analyses

YesWeLab collaborates with a network of more than 200 partner laboratories in France and Europe, carefully selected for their expertise, certifications, and accreditations (ISO 17025, COFRAC, etc.). Our scientific team assists you in defining the analytical method best suited to your samples and objectives. Thanks to our digital platform, you benefit from a simplified service: rapid quote requests, online sample tracking, and receipt of results within the agreed deadlines. Many manufacturers, distributors, and design offices already trust us to centralize and optimize their analyses.

Take action

Do you want to analyze your valerian extracts or nutraceutical products containing valerenic acids? Entrust your samples to YesWeLab for reliable quality control that complies with regulatory requirements. Request a quote online now for your valerenic acid assay.