Dosage of tetracyclines and tylosin

Tetracyclines and tylosin are antibiotics commonly used in veterinary medicine to prevent or treat bacterial infections. Their extensive use in livestock farming can lead to the presence of residues in foodstuffs of animal origin such as meat, milk, eggs, and fish. These residues, strictly regulated within the European Union, must be monitored to ensure food safety and limit the risks associated with antibiotic resistance. The measurement of tetracyclines and tylosin is therefore an essential step for food manufacturers.

Analytical methods for the determination of tetracyclines and tylosin

The analysis of these antibiotics is based on sensitive and multi-residue techniques:

• HPLC (high performance liquid chromatography), used to separate different molecules and obtain overall quantification.
• LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry), the reference technique for detecting and quantifying these compounds at very low concentrations.

These methods meet the requirements of Regulation (EC) No 37/2010, which sets maximum residue limits (MRLs) in foodstuffs. They are comparable to those used for the determination of sulfonamides or streptomycins , which are also essential for the health control of animal products.

Industrial and regulatory applications

The dosage of tetracyclines and tylosin is suitable for several industrial contexts:

• Human food: verification of the conformity of meat, eggs, fish and dairy products.
• Animal production: monitoring of veterinary practices and compliance with waiting times before slaughter or collection.
• Distribution and export: compliance with international regulations and customer specifications.
• Research laboratories: monitoring the impact of antibiotic treatments on the quality of animal products.

These analyses are essential to secure the sectors and reassure consumers.

Matrices analyzed for tetracyclines and tylosin

YesWeLab supports the analysis of these antibiotics in various matrices: fresh and processed meat, fish and seafood, eggs, milk and dairy products. Each matrix is ​​prepared according to a specific protocol to ensure the reliability and reproducibility of the results.

Quality and compliance issues

The presence of tetracycline and tylosin residues raises several major issues:

• Protecting public health by reducing exposure to antibiotics.
• Preventing antibiotic resistance, a global health problem.
• Strict compliance with the MRLs defined by European regulations.
• Maintaining the competitiveness of animal sectors through traceability and rigorous control.

These issues are similar to those addressed in the context of nitrosamine or heavy metal testing , which also contribute to the safety of food products.

YesWeLab's expertise in antibiotic residue measurement

YesWeLab relies on a network of more than 200 partner laboratories in France and Europe, accredited ISO 17025 and COFRAC. Our experts assist you in choosing the method best suited to your matrices and needs (quality control, regulatory compliance, certification, or export). Thanks to our digital platform, you benefit from a simplified and rapid service: online quote request, sample tracking, and return of results within optimized timeframes. Since 2020, numerous manufacturers and distributors have entrusted us with their residue analyses to guarantee the safety of their sectors.

Take action

Do you want to check your food for tetracyclines and tylosin? Entrust your testing to YesWeLab for accurate, fast, and compliant results. Request a quote online today.