Dosage of terpinen-4-ol

The dosage of terpinen-4-ol allows the quantification of this bioactive monoterpenol present mainly in tea tree essential oil (Melaleuca alternifolia) . This compound is recognized for its antibacterial, antifungal, anti-inflammatory and antiseptic properties , which makes it a key marker of the quality and effectiveness of essential oils.

This analysis aims to authenticate essential oils and to standardize cosmetic, pharmaceutical or antiseptic formulations containing terpinen-4-ol.

Analytical methods

The dosage is carried out by gas chromatography , using two main approaches:

• GC-FID (flame ionization detector) : reference method for the accurate and reproducible quantification of terpinen-4-ol in simple matrices.
• GC-MS (gas chromatography coupled with mass spectrometry) : specific identification of terpinen-4-ol within a complex mixture, particularly in multi-component essential oils or finished products.

ISO 4730 , AFNOR NF T75-006 or European Pharmacopoeia standards , guaranteeing the reliability of the results and compliance with international standards.

Industrial applications

The analysis of terpinen-4-ol is essential in several sectors:

• Nutraceuticals : standardization of plant extracts and essential oils for antimicrobial purposes.
• Cosmetics : verification of the terpinen-4-ol content in lotions, creams, gels or purifying shampoos.
• Phytotherapy and aromatherapy : authentication of essential oils of tea tree or other plants rich in terpenes.
• Hygiene and animal health : formulation of natural antiseptic products or mild disinfectants.

Analyzed matrices

• Pure essential oils (tea tree, lavender, eucalyptus, etc.)
• Cosmetic products (gels, creams, shampoos, lotions)
• Food supplements based on plant extracts
• Pharmaceutical products and natural antiseptics

Further analyses recommended

For a complete characterization of the chemical profile of essential oils, YesWeLab recommends combining:

• Dosage of 1,8-cineole : terpene compound with respiratory and anti-inflammatory properties,
• Limonene determination : analysis of one of the main volatile monoterpenes,
• Dosage of thymol : another aromatic compound with antiseptic effect,

YesWeLab expertise

Thanks to its network of ISO 17025 and COFRAC accredited laboratories , YesWeLab supports you in the quality control , standardization and regulatory validation of your natural products and aromatic formulations.
Our digital platform simplifies the ordering of analyses , the tracking of samples and the consultation of reports , in order to guarantee complete traceability and optimal compliance with your requirements.

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