Costunolide (sesquiterpene lactone) dosage

Costunolide is a sesquiterpene lactone found in several plant species, including elecampane (Inula helenium) and other medicinal plants of the Asteraceae family. This natural compound is known for its anti-inflammatory and cytotoxic properties, making it a molecule of interest in the field of phytotherapy and nutraceuticals.

Costunolide dosing helps ensure the standardization of plant extracts, ensure regulatory compliance, and scientifically demonstrate the efficacy of herbal products.

Importance of dosage

Costunolide content can vary depending on the botanical origin, cultivation conditions, extraction process and storage of raw materials. Reliable quantification is therefore necessary for:

• standardize medicinal plant extracts
• ensure the reproducibility of nutraceutical formulations
• demonstrate the efficacy and quality of finished products
• meet regulatory requirements for safety and compliance
• strengthen consumer confidence through transparent analytical data

This analysis is particularly useful for manufacturers of food supplements, distributors and design offices specializing in plant extracts.

Available analytical methods

The dosage of costunolide is based on high-precision chromatographic techniques adapted to complex plant matrices:

• HPLC (high-performance liquid chromatography): the reference method for the separation and quantification of costunolide. It allows reproducible and reliable measurement even at low concentrations.
• LC-MS (liquid chromatography coupled with mass spectrometry): an advanced method, allowing not only to confirm the molecular identity of costunolide but also to detect other sesquiterpene lactones present in the extracts.

These approaches guarantee results adapted to industrial and regulatory requirements.

Affected matrices

Costunolide dosage can be performed in different plant matrices and derived products:

• root extracts (especially elecampane)
• plant powders used in phytotherapy
• food supplements in the form of capsules or tablets
• complex nutraceutical preparations containing several natural active ingredients

This analysis is applicable to both raw materials and finished products, guaranteeing complete control of the production chain.

Industrial and scientific applications

Costunolide dosage is essential for various industrial and scientific players:

• in nutraceuticals and phytotherapy, it ensures the standardization of extracts and the conformity of formulations
• in research, it allows the biological effects of costunolide to be evaluated, in particular its anti-inflammatory and anti-
• for distributors and importers, it guarantees the safety of batches and limits the risks of regulatory non-compliance
• for development laboratories, it contributes to innovation by identifying the content of active molecules in plant extracts

Additional analyses available

To complete the analytical profile of plant extracts, YesWeLab offers the dosage of other sesquiterpene lactones and associated bioactive compounds:

Alantolactone dosage
Quercetin (flavonoid) dosage
Rutin (flavonoid) dosage

These services enable us to obtain a complete characterization of plant extracts and to strengthen their scientific and commercial value.

YesWeLab expertise

YesWeLab relies on a network of partner laboratories specialized in physicochemical and plant analyses, rigorously selected and for the most part ISO 17025 certified and COFRAC accredited.

Since 2020, our digital platform has been supporting manufacturers, distributors, and design offices in managing their analyses. It centralizes requests, simplifies sample tracking, and guarantees reliable and fast results.

Our scientific team strives to meet the specific needs of clients in terms of quality control, standardization and regulatory compliance.