Dosage of rosarin, rosavin, rosin, salidroside

Rosarin, rosavin, rosin, and salidroside are phenolic compounds specific to the Rhodiola rosea , known for its adaptogenic and anti-stress properties. Their dosage allows for the evaluation of the authenticity, quality, and concentration of plant extracts used in dietary supplements or natural formulations.

Rhodiola rosea -based products , often standardized in rosavines and salidroside, two indicators of purity and efficacy recognized in European regulations and pharmacopoeias.

Principle and operation of the method

The analysis relies on the selective extraction of phenolic compounds from plant matrices such as powders, dry extracts, capsules, herbal teas, or tinctures. The sample is then injected into an HPLC or LC-MS , depending on the level of precision required.

In HPLC-DAD, compounds are separated according to their polarity and detected by UV absorption. LC-MS offers superior sensitivity and allows the identification of each molecule based on its exact mass, ensuring reliable results, even in complex or low-concentration extracts.

This approach ensures a clear identification of the characteristic markers of Rhodiola rosea , and allows the detection of possible falsifications by plant substitution.

Analytical performance and related analyses

HPLC and LC-MS methods offer excellent sensitivity, high specificity and reproducibility suitable for the requirements of quality control and research.

For a complete characterization of plant extracts, this analysis can be combined with other services from the YesWeLab catalogue, such as:

• the dosage of total flavonoids ,
• the dosage of total polyphenols ,
• the dosage of rosin alone ,
• the dosage of pure salidroside ,
• or the dosage of tyrosol and p-tyrosol , also present in some Rhodiola species.

These additional analyses make it possible to obtain a complete phytocompound profile and to confirm the botanical origin of the extracts.

Applications and areas of use

The measurement of rosarine, rosavin, rosin, and salidroside is applicable in several contexts:

• Nutraceutical Rhodiola rosea extracts to ensure their adaptogenic and antioxidant efficacy.
• Quality control : verification of batch conformity according to pharmacopoeia monographs and manufacturer specifications.
• Research & development : study of variations in composition according to geographical origin, growing conditions and extraction processes.
• Phytotherapy and formulation : optimization of the synergy between rosavines and salidroside in products intended for anti-stress or tonic purposes.

These dosages help to strengthen the traceability and scientific value of Rhodiola rosea .

The advantages of the YesWeLab service

YesWeLab collaborates with a network of partner laboratories accredited to ISO 17025 and COFRAC standards, experts in phytochemical analysis and the characterization of plant extracts. Each request is directed to the most suitable laboratory based on the matrix, method, and analytical objectives.

Thanks to its digital platform, YesWeLab simplifies the management of analyses: requesting quotes, sending samples, online tracking, and receiving results quickly. Since 2020, numerous players in the nutraceutical and phytotherapy sectors have trusted us for the control and standardization of their plant extracts.

Rhodiola rosea markers , contact our scientific team to obtain a personalized quote and technical support tailored to your needs.