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Dosage of quercetin-3-O-gentiobiside

Dosage of quercetin-3-O-gentiobiside

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

7431-83-6

Description

Quercetin-3-O-gentiobiside is a glycosylated derivative of quercetin, naturally present in several medicinal plants, notably St. John's wort (Hypericum perforatum). It is studied for its antioxidant properties and its contribution to the overall biological activity of plant extracts.

Quercetin-3-O-gentiobiside levels are essential for:

  • Standardize plant extracts used in nutraceuticals
  • Monitor quality markers in dietary supplements
  • Control the concentration of glycosylated flavonoids in finished products

Available analytical methods

The analysis is performed according to the complexity of the matrix:

  • HPLC-DAD: a robust method for simple or standardized extracts
  • LC-MS/MS: recommended for complex or enriched products, with specific detection of glycosides

Affected matrices

This assay is suitable for the following samples:

  • Dry or purified extracts of St. John's wort or other flavonoid-rich plants
  • Infusions, plant powders, capsules or tablets
  • Standardized products with antioxidant or relaxing properties
  • Nutraceutical mixtures containing glycosylated flavonoids

Industrial interests

The analysis of quercetin-3-O-gentiobiside is particularly relevant for:

  • Manufacturers of St. John's wort-based food supplements
  • Laboratories specializing in herbal medicine and botanical extracts
  • Plant-based cosmetics companies seeking natural active ingredients
  • R&D project leaders in nutrition, health, and standardized extracts

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