Quercetin-3-methyl ether assay

Quercetin-3-methylether, also known as isorhamnetin, is a methylated form of quercetin, naturally present in certain medicinal plants such as sea buckthorn, wild garlic, and red onions. This molecule is distinguished by its improved bioavailability, enhanced oxidative stability, and promising antioxidant and anti-inflammatory activity.

Quercetin-3-methyl ether measurement is essential for:

• Standardize plant extracts enriched with methylated flavonoids
• Validating functional claims in food supplements
• Monitor the concentration in products intended for cardiovascular or immune function

Analytical methods

The analysis is based on two reference techniques:

• HPLC-DAD: UV absorption detection, suitable for simple or standardized matrices
• LC-MS/MS: specific and sensitive quantification in complex extracts or finished products

Affected matrices

This dosage applies to various types of matrices:

• Raw or purified plant extracts
• Dietary supplements in the form of capsules, tablets or powders
• Innovative formulations containing methylated flavonoids (beverages, nutraceutical blends)
• High value-added plant-based enriched products

Industrial applications

Quercetin-3-methyl ether measurement is particularly useful for:

• Manufacturers of dietary supplements based on functional flavonoids
• Phytotherapy or active nutrition laboratories
• Players in the plant-based cosmetics industry, particularly in the formulation of antioxidant active ingredients
• R&D projects on highly bioavailable forms of polyphenols

Recommended Related Analyses

• Quercetin assay – to compare the methylated and unmethylated forms
• Isorhamnetin assay – another name used for quercetin-3-methyl ether
• Total flavonoid content – ​​for a comprehensive approach to plant extracts

Why choose YesWeLab?

• A network of expert laboratories specializing in the analysis of plant compounds and nutritional actives
• A personalized approach tailored to your matrix and quality objectives
• A digital platform to simplify ordering and tracking your analyses
• Scientific support for your standardization, development, or compliance projects

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