Dosage of luteolin-7-O-glucoside

Luteolin-7-O-glucoside is a flavonoid glycoside molecule derived from luteolin. Naturally present in many medicinal plants, this conjugated form is particularly abundant in chamomile, artichoke, and olive leaves. Known for its antioxidant, anti-inflammatory, and protective properties, it is often used as an analytical marker in nutraceutical and cosmetic extracts.

The dosage of luteolin-7-O-glucoside is essential for the standardization of plant extracts, the quality control of raw materials or even the verification of compositions in finished products.

Methodology: reliable analysis by HPLC or LC-MS

Luteolin-7-O-glucoside analysis is performed by high-performance liquid chromatography (HPLC) or liquid chromatography-mass spectrometry (LC-MS). These methods ensure accurate quantification, even in complex matrices and at low concentrations.

Analytical steps include:

• Sample preparation optimized according to the nature of the matrix (infusion, dry extract, liquid, plant powder, etc.)
• Selective chromatographic separation
• Detection by UV-DAD or MS/MS, depending on the required sensitivity and specificity

The methods are validated according to the standards of good analytical practices, in accordance with the requirements of ISO 17025 or the COFRAC standard for physicochemical analyses.

Affected matrices

The dosage of luteolin-7-O-glucoside applies to different plant matrices or formulations, including:

• Hydroalcoholic or aqueous extracts of medicinal plants
• Infusions, decoctions, galenic preparations based on plants
• Food supplements in the form of capsules, tablets or powders
• Plant raw materials intended for cosmetics or nutraceuticals
• Industrial and regulatory applications

Luteolin-7-O-glucoside analysis is recommended for:

• Standardization of extracts of chamomile, artichoke, thyme, rosemary, etc.
• The development of antioxidant products based on natural flavonoids
• Stability and traceability studies of plant active ingredients
• Control of the conformity of ingredients of natural origin in cosmetic and nutraceutical products

This analysis is also used in comparative studies of bioavailability and biological activity of glycosylated flavonoids vs. aglycones.

Internal links to other flavonoid analyses

To complete your analyses, also discover:

• Luteolin assay – to compare free and glycosylated forms
• Luteolin-7-glucuronide assay – for metabolism studies
• Dosage of apigenin – another flavonoid found in chamomile
• Determination of total flavonoids – global method for complex extracts

Why use YesWeLab for your flavonoid analyses?

YesWeLab relies on a network of accredited partner laboratories (ISO 17025, COFRAC, etc.) selected for their expertise in the analysis of phytochemical compounds. Our scientific team assists you in defining your analytical protocol, optimizing extraction conditions, choosing methods, and interpreting results.

Our digital platform allows you to centralize all your analysis requests, track your samples in real time, and access your reports via a secure space.

Need a luteolin-7-O-glucoside dosage?

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