Luteolin-7-glucuronide assay

Luteolin -7-glucuronide is a conjugated form of luteolin, a flavonoid widely found in plant extracts. This glucuronidated metabolite is produced naturally by certain plants or generated after hepatic biotransformation in humans or animals. It is attracting increasing interest in the nutraceutical and phytotherapeutic sectors due to its antioxidant, anti-inflammatory, and neuroprotective properties.

Luteolin-7-glucuronide measurement allows for a better understanding of the bioavailability of plant extracts, the evaluation of their pharmacological efficacy, and the monitoring of their traceability in processed or formulated products. It is therefore an essential analytical marker in clinical studies, the standardization of extracts, or the quality control of flavonoid-based food supplements.

Analyzed matrices

The determination of luteolin-7-glucuronide can be carried out on many matrices, including:

• Crude or standardized plant extracts (e.g. leaves, flowers, fruits)
• Food supplements enriched with flavonoids
• Biological samples from pharmacokinetic studies (sera, urine, etc.)
• Products of fermentation or industrial extraction

Industrial and scientific applications

This analysis is of great interest for:

• Standardization of medicinal plant extracts, in relation to the content of active metabolites
• Evaluation of stability and metabolic transformation of flavonoids in complex formulations
• Clinical or preclinical studies of bioavailability and efficacy
• Analytical traceability of certain ingredients in processed products

Luteolin-7-glucuronide is particularly studied in extracts of plantain, chamomile, thyme or olive , where it can represent a marker of quality or authenticity.

Useful links to additional analyses

For a comprehensive approach to the characterization of flavonoids or their metabolites, also discover our services:

• Luteolin dosage 
• Apigenin dosage
• Total flavonoids assay 

Why choose YesWeLab?

YesWeLab provides you with a network of partner laboratories, selected for their expertise, certifications (ISO 17025, COFRAC, etc.), and ability to process complex matrices. Thanks to our digital platform, you can centralize your analysis requests, track the progress of your files, and receive your results as quickly as possible.

Since 2020, YesWeLab has been supporting manufacturers, formulators and distributors of supplements in their analysis, validation and compliance projects.

Contact our scientific team

Interested in analyzing luteolin-7-glucuronide in your extracts, finished products, or biological matrices?
Contact our team now for a personalized quote or a customized technical study.