Luteolin-7-glucuronide assay

Luteolin -7-glucuronide is a conjugated form of luteolin, a flavonoid widely found in plant extracts. This glucuronide metabolite is produced naturally by certain plants or generated after hepatic biotransformation in humans and animals. It is attracting increasing interest in the nutraceutical and phytotherapeutic sectors due to its antioxidant, anti-inflammatory, and neuroprotective properties.

Measuring luteolin-7-glucuronide levels allows for a better understanding of the bioavailability of plant extracts, the evaluation of their pharmacological efficacy, and the monitoring of their traceability in processed or formulated products. It is therefore an essential analytical marker in clinical studies, the standardization of extracts, and the quality control of flavonoid-based dietary supplements.

Analyzed matrices

Luteolin-7-glucuronide can be measured in numerous matrices, including:

• Raw or standardized plant extracts (e.g., leaves, flowers, fruits)
• Flavonoid-enriched dietary supplements
• Biological samples from pharmacokinetic studies (serum, urine, etc.)
• Products of industrial fermentation or extraction

Industrial and scientific applications

This analysis is of great interest because:

• The standardization of medicinal plant extracts, in relation to the content of active metabolites
• Evaluation of the stability and metabolic transformation of flavonoids in complex formulations
• Clinical or preclinical studies of bioavailability and efficacy
• Analytical traceability of certain ingredients in processed products

Luteolin-7-glucuronide is studied in particular in extracts of plantain, chamomile, thyme or olive , where it can represent a marker of quality or authenticity.

Useful links to further analyses

For a comprehensive approach to the characterization of flavonoids or their metabolites, discover our other services:

• Luteolin assay 
• Apigenin assay
• Total flavonoid content assay 

Why choose YesWeLab?

YesWeLab provides you with a network of partner laboratories, selected for their expertise, certifications (ISO 17025, COFRAC, etc.), and ability to process complex matrices. Our digital platform allows you to centralize your analysis requests, track the progress of your files, and receive your results as quickly as possible.

Since 2020, YesWeLab has been supporting manufacturers, formulators and distributors of supplements in their analysis, validation and compliance projects.

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