Dosage of jujuboside A (saponoside / saponin)

The measurement of jujuboside A allows for the quantification of triterpene saponins characteristic of the jujube tree ( Ziziphus jujuba ), a medicinal plant used since antiquity in Asian pharmacopoeia. These active compounds, notably jujuboside A and jujuboside B, are recognized for their calming, sedative, and neuroprotective properties.

nutraceutical and phytotherapy stakeholders to guarantee the quality, standardization and conformity of jujube extracts or finished products.

Jujuboside A: a bioactive saponin from the jujube tree

Jujuboside A (CAS No. 19564672) is a glycosidic saponin belonging to the oleanane triterpene family. It is concentrated primarily in the seeds of Ziziphus jujuba , also known as Chinese dates. Its complex chemical structure gives it a variety of biological properties: a calming effect on the central nervous system, anxiety reduction, improved sleep, and antioxidant activity.

In the nutraceutical field, this molecule is used as a quality marker for standardized jujube extracts. Its quantification is essential to verify the conformity of raw materials, control extract batches, and guarantee the functional efficacy of finished products.

Objectives of jujuboside A assay

The assay of jujuboside A is applicable to many analytical situations:

• quality control of dry extracts, hydroalcoholic or standardized in saponins,
• standardization of nutraceutical and phytotherapeutic products,
• verification of the conformity of plant-based raw materials to the pharmacopoeia,
• monitoring of stability and bioavailability in complex formulations,
• validation of functional claims related to well-being, sleep or relaxation.

This analysis also makes it possible to differentiate between authentic extracts of Ziziphus jujuba and products of uncertain origin, thanks to the specific chromatographic signature of jujuboside A.

Analytical methods used

The measurement of jujuboside A relies on high-performance chromatographic techniques adapted to the detection of complex and polar molecules:

• HPLC (high-performance liquid chromatography) : the reference method for quantifying saponins in plant extracts. It allows for the precise measurement of jujuboside A concentration after extraction and purification.
• LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry) : offers superior sensitivity and selectivity, allowing identification of jujuboside A and its derivatives even at very low concentrations in complex matrices.

These methods guarantee the reproducibility of results and compliance with good laboratory practice requirements. Depending on the type of sample, a preliminary extraction and purification step is carried out to isolate the saponins from other plant compounds (polyphenols, sugars, organic acids).

This analysis can be combined with other services from the YesWeLab catalogue, such as the determination of total saponins , the determination of ginsenoside , or the determination of Indian ginseng (ashwagandha) , in order to obtain a complete evaluation of the bioactive compounds present in adaptogenic extracts.

Sectors and matrices concerned

The measurement of jujuboside A is relevant to several areas:

• Nutraceuticals and phytotherapy : verification of the quality and standardization of jujube extracts used in food supplements intended for relaxation or sleep.
• Botanical and pharmacological research Ziziphus jujuba extracts from different geographical origins.
• Plant ingredients industry : quality control of batches of extracts standardized in saponins, to guarantee the consistency of the formulas.
• Natural and cosmetic products : use of jujuboside as a marker of purity and authenticity of botanical extracts incorporated into soothing skincare.

This service is part of a broader analytical offering provided by YesWeLab, including, for example, the measurement of flavonoids , the measurement of total polyphenols , or the measurement of alkaloids, for a complete evaluation of the phytochemical profile of plant extracts.

Analysis performed at YesWeLab

YesWeLab entrusts the measurement of jujuboside A to partner laboratories specializing in the chromatographic analysis of plant compounds. These laboratories are equipped with state-of-the-art HPLC and LC-MS/MS instruments and apply protocols compliant with ISO 17025 and COFRAC standards.

Our scientific team assists manufacturers, formulators, and extract producers in selecting the most suitable method for their needs: specific assays, multi-saponin testing, or stability studies. Thanks to the YesWeLab digital platform, analysis management is simplified: online submission, real-time sample tracking, and secure receipt of analytical reports.

Since 2020, numerous players in the nutraceutical, phytotherapy, and plant research sectors have trusted YesWeLab for the characterization of their natural extracts. Our approach guarantees reliable results, regulatory compliance, and complete data traceability.

Technical data

• CAS No.: 19564672
• Methods: HPLC, LC-MS/MS
• Expertise: Physico-chemical, nutritional
• Business sectors: Nutraceuticals, plants
• Measured parameters: Jujuboside A and saponin derivatives

For any specific request or need for further analysis, contact our team now to obtain a personalized quote and recommendations tailored to your plant samples.