Dosage of jujuboside A (saponoside / saponin)

The dosage of jujuboside A allows the quantification of triterpene saponins characteristic of jujube ( Ziziphus jujuba ), a medicinal plant used since ancient times in Asian pharmacopoeia. These active compounds, notably jujuboside A and jujuboside B, are recognized for their soothing, sedative and neuroprotective properties.

nutraceutical and phytotherapy players , in order to guarantee the quality, standardization and conformity of extracts or finished products based on jujube.

Jujuboside A: a bioactive saponin from jujube

Jujuboside A (CAS No. 19564672) is a glycosidic saponin belonging to the oleananic triterpene family. It is mainly concentrated in the seeds of Ziziphus jujuba , also known as Chinese dates. Its complex chemical structure gives it various biological properties: calming effect on the central nervous system, reducing anxiety, improving sleep and antioxidant action.

In the nutraceutical field, this molecule is used as a quality marker for standardized jujube extracts. Its quantification is essential to verify the conformity of raw materials, control batches of extracts and guarantee the functional efficacy of finished products.

Objectives of jujuboside A dosage

The dosage of jujuboside A applies to many analytical situations:

• quality control of dry, hydroalcoholic or saponin-based extracts,
• standardization of nutraceutical and phytotherapeutic products,
• verification of the conformity of plant raw materials to the pharmacopoeia,
• monitoring of stability and bioavailability in complex formulations,
• validation of functional claims on well-being, sleep or relaxation.

This analysis also allows the differentiation between authentic Ziziphus jujuba and products of uncertain origin, thanks to the specific chromatographic signature of jujuboside A.

Analytical methods used

The dosage of jujuboside A is based on high-performance chromatographic techniques adapted to the detection of complex and polar molecules:

• HPLC (high-performance liquid chromatography) : the reference method for quantifying saponins in plant extracts. It allows precise measurement of jujuboside A concentration after extraction and purification.
• LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry) : offers superior sensitivity and selectivity, allowing the identification of jujuboside A and its derivatives even at very low concentrations in complex matrices.

These methods ensure reproducibility of results and compliance with the requirements of good laboratory practices. Depending on the type of sample, a preliminary extraction and purification step is carried out to isolate saponins from other plant compounds (polyphenols, sugars, organic acids).

This analysis can be combined with other services from the YesWeLab catalog, such as the dosage of total saponins , the dosage of ginsenoside , or the dosage of Indian ginseng (ashwagandha) , in order to obtain a complete evaluation of the bioactive compounds present in the adaptogenic extracts.

Sectors and matrices concerned

The dosage of jujuboside A concerns several areas:

• Nutraceuticals and phytotherapy : verification of the quality and standardization of jujube extracts used in food supplements intended for relaxation or sleep.
• Botanical and pharmacological research : characterization of the chemical profile of Ziziphus jujuba from different geographical origins.
• Plant ingredient industry : quality control of batches of extracts titrated in saponins, to guarantee the consistency of the formulas.
• Natural products and cosmetics : use of jujuboside as a marker of purity and authenticity of botanical extracts integrated into soothing treatments.

This service is part of a broader analytical offering proposed by YesWeLab, including for example the dosage of flavonoids , the dosage of total polyphenols , or the dosage of alkaloids, for a complete evaluation of the phytochemical profile of plant extracts.

Carrying out analyses at YesWeLab

YesWeLab entrusts the determination of jujuboside A to partner laboratories specialized in the chromatographic analysis of plant compounds. These laboratories are equipped with the latest generation of HPLC and LC-MS/MS instruments and apply protocols compliant with ISO 17025 and COFRAC standards.

Our scientific team supports manufacturers, formulators, and extract producers in selecting the method best suited to their needs: specific dosage, multi-saponins, or stability studies. Thanks to the YesWeLab digital platform, analysis management is simplified: online submission, real-time sample tracking, and secure receipt of analytical reports.

Since 2020, numerous players in the nutraceutical, phytotherapy, and plant research sectors have trusted YesWeLab to characterize their natural extracts. Our approach guarantees reliable results, regulatory compliance, and complete data traceability.

Technical data

• CAS No.: 19564672
• Methods: HPLC, LC-MS/MS
• Expertise: Physicochemical, nutritional
• Sectors of activity: Nutraceuticals, plants
• Measured parameters: Jujuboside A and saponin derivatives

For any specific requests or additional analysis needs, contact our team now to obtain a personalized quote and recommendations tailored to your plant samples.