Geniposide (iridoid glycoside) dosage

Geniposide (CAS No. 24512-63-8) is an iridoid glycoside naturally present in the fruit of the gardenia ( Gardenia jasminoides ) , a plant widely used in Asian pharmacopoeia . This compound is recognized for its anti-inflammatory, antioxidant, and hepatoprotective properties , contributing to liver protection and the regulation of metabolic processes.

Geniposide analysis allows for the precise quantification of the active ingredient content in gardenia-based extracts, powders, or formulations. This analysis is essential for the standardization of plant extracts , ensuring the quality of raw materials , and validating nutraceutical claims .

Analytical methods: HPLC-DAD and LC-MS

Geniposide is analyzed using high-precision chromatographic techniques:

• HPLC-DAD (high-performance liquid chromatography with diode array detection) : a method commonly used for the separation and quantification of iridoids and other natural glycosides.
• LC-MS (liquid chromatography coupled with mass spectrometry) : reference technique for finer detection and specific molecular identification of geniposide and its derivatives.

These approaches guarantee reliable, reproducible quantification that complies with the requirements of pharmacopoeias and international standards (ISO, AOAC) .

Industrial and scientific applications

Geniposide analysis is essential in several fields:

• Nutraceutical industry : standardization of Gardenia jasminoides to guarantee the consistency of the active profile.
• Phytotherapy : quality control of iridoid-based preparations to ensure their efficacy and safety.
• Scientific research : evaluation of the biological activity and hepatoprotective or anti-inflammatory properties of geniposide.
• Control of plant-based raw materials : verification of the conformity of extracts used in the formulation of finished products.

This analysis can be complemented by the measurement of total iridoids or by the measurement of gypenoside XVII , in order to more broadly characterize the phytochemical profile of the plant extracts.

Affected matrices

Our partner laboratories perform geniposide assays on a wide variety of matrices:

• Dry or fluid extracts of Gardenia jasminoides
• Standardized vegetable powders
• Dietary supplements in the form of capsules, tablets or liquids
• Phytotherapeutic preparations and complex nutraceutical formulations

Depending on the matrix, analytical protocols can be adapted to optimize compound recovery and the reliability of results.

YesWeLab expertise

At YesWeLab , we work with an international network of over 200 partner laboratories in France, Europe and internationally , selected for their analytical expertise and their ISO 17025 and COFRAC accreditation .

Our scientific team supports you throughout the entire process: laboratory selection , choice of the most suitable method , sample tracking , and results interpretation . Thanks to our digital platform , you can centralize your requests , compare analysis options , and track your services with complete transparency .

Since 2020, many manufacturers, formulators and distributors have trusted us to ensure the quality, traceability and compliance of their plant analyses.

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