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Ferulic acid (hydroxycinnamic acid) dosage

Ferulic acid (hydroxycinnamic acid) dosage

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

1135-24-6

Description

Ferulic acid is a hydroxycinnamic acid widely found in the plant kingdom, particularly in cereals (rice, wheat, corn, oats), fruits, and certain vegetables. This phenolic compound is distinguished by its powerful antioxidant activity, capable of neutralizing free radicals and protecting cellular structures against oxidative stress.

It is frequently used in the nutraceutical and cosmetic industries for its protective, soothing, and anti-aging effects. In plant extracts, ferulic acid also acts as a stabilizer for vitamin C and vitamin E, thus prolonging the effectiveness of antioxidant formulations.

Ferulic acid analysis is therefore an essential analytical tool for assessing the quality of plant-based raw materials, the conformity of formulations, and the functional effectiveness of finished products.

Advantages of analytical measurement

Ferulic acid levels allow us to:

  • Measuring the phenolic compound content in plant extracts and functional ingredients.
  • To guarantee the quality and standardization of extracts from cereals, fruits or medicinal plants.
  • Evaluate the antioxidant potential of nutraceutical or cosmetic products.
  • Control the stability of formulations enriched with polyphenols or vitamins.
  • Identify the presence of ferulic acid in natural, food or technical matrices.

This analysis is particularly useful for characterizing antioxidant-rich extracts used in anti-aging products, cardiovascular supplements, or protective skin care products.

Analytical methods used

At YesWeLab, ferulic acid quantification is performed by high-performance liquid chromatography (HPLC-DAD) or by liquid chromatography coupled with mass spectrometry (LC-MS or LC-MS/MS).

HPLC-DAD Chromatography:
HPLC with diode array detection (DAD) is a reference method for separating ferulic acid from other phenolic acids present in extracts. This approach provides reliable and reproducible results, particularly suited to routine control.

LC-MS / LC-MS-MS Chromatography:
Coupling liquid chromatography with mass spectrometry allows for specific and highly sensitive detection of ferulic acid, even at low concentrations. This method is preferred for complex matrices (cosmetics, multi-active extracts, enriched products).

The analyses are carried out according to protocols that comply with ISO 17025 requirements, guaranteeing maximum reliability and perfect traceability of results.

Industrial and sectoral applications

Nutraceutical:
Ferulic acid is commonly used as an active ingredient in dietary supplements intended for cell protection, prevention of premature aging, and inflammation reduction. Its dosage allows for control of the quality of natural extracts and the concentration of active ingredients.

cosmetics,
ferulic acid works synergistically with vitamins C and E in anti-aging and photoprotective skincare to strengthen the skin's antioxidant defenses. Analysis ensures the stability and efficacy of formulations, particularly in serums and anti-free radical creams.

Agri-food and botany
In products derived from cereals or medicinal plants, the measurement of ferulic acid makes it possible to monitor the bioavailability of phenolic compounds, to assess nutritional potential and to optimize extraction processes.

Research and quality control
Research laboratories use this analysis to characterize polyphenolic profiles and compare ferulic acid levels according to botanical origin or processing method.

Affected matrices

  • Extracts of rice, wheat, corn and oats
  • Antioxidant food supplements
  • Anti-aging serums and creams
  • Standardized vegetable powders
  • Products enriched with polyphenols

Recommended Related Analyses

For a comprehensive approach to phenolic characterization, YesWeLab recommends combining the following:
Caffeic acid assay – another structurally similar hydroxycinnamic acid.
Coumaric acid assay – complementary for the overall antioxidant profile.
Caftaric acid assay – for extracts based on red vine and grape.
Total polyphenol assay – to assess overall antioxidant richness.

Why choose YesWeLab?

YesWeLab relies on a network of ISO 17025 and COFRAC accredited laboratories specializing in the characterization of phenolic compounds and natural antioxidants.
Our experts support nutraceutical, cosmetic, and research companies in standardizing their extracts and ensuring their products comply with regulations.
Our digital platform makes ordering, tracking, and receiving analysis results simple, fast, and completely secure.

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