Dihydrokavain (kavalactone) dosage

Dihydrokavain is one of the main kavalactones found in kava (Piper methysticum), a plant native to the Pacific traditionally used for its relaxing and anxiolytic effects. Kavalactones, including dihydrokavain, are the bioactive molecules responsible for kava's pharmacological and nutraceutical properties.

Dihydrokavain measurement is an essential step in controlling the content of active ingredients in kava extracts and products formulated with this plant. It helps ensure the standardization, safety, and efficacy of food supplements, beverages, and herbal preparations intended for the market.

Importance of dosage

Kava consumption is regulated in many countries due to the need to precisely control its composition. Quantifying dihydrokavain provides manufacturers and distributors with:

• control of the concentration of kavalactones in extracts
• regulatory compliance of products on the nutraceutical market
• reproducibility of formulations to guarantee efficacy and safety
• scientific and commercial promotion of finished products

Accurate dosage is essential to ensure transparency for consumers and demonstrate the quality of natural health products and food supplements.

Available analytical methods

The determination of dihydrokavain is based on high-performance chromatographic techniques, suitable for the quantification of kavalactones in complex matrices.

• HPLC-DAD (high performance liquid chromatography with diode array detection): reference method for separating and quantifying kavalactones with excellent precision.
• LC-MS (liquid chromatography coupled with mass spectrometry): complementary method offering high sensitivity and allowing confirmation of the molecular identity of dihydrokavain, while detecting other kavalactones present in the extract.

These approaches guarantee reliable, reproducible results adapted to the requirements of manufacturers in the nutraceutical sector.

Affected matrices

Dihydrokavain assay can be performed in various matrices, including:

• standardized dry kava extracts
• kava root powders or formulations
• nutraceutical capsules and tablets
• plant-based drinks and liquid preparations

This analysis is suitable for both raw materials and finished products, ensuring complete monitoring of the production chain.

Industrial applications

Dihydrokavain assay results are essential for dietary supplement manufacturers, distributors, and design offices. They allow you to:

• ensure product compliance with current regulations
• assess the potential effectiveness of kava extracts based on their kavalactone content
• secure the marketing of products intended for relaxation and well-being
• strengthen the traceability and quality of production batches

This analysis is part of a global approach to quality control and scientific promotion of natural products.

Additional analyses available

YesWeLab offers other services to complete the analytical profile of kava extracts and strengthen their standardization. These include:

Quercetin (flavonoid) dosage

These complementary analyses make it possible to obtain a complete spectrum of the bioactive compounds present in kava and to optimize the formulation of nutraceutical products.

YesWeLab expertise

YesWeLab relies on a network of partner laboratories specialized in physicochemical and nutraceutical analyses, rigorously selected and for the most part ISO 17025 certified and COFRAC accredited.

Since 2020, our digital platform has simplified analysis management for manufacturers, distributors, and design offices. It allows you to centralize requests, track sample progress, and receive reliable results as quickly as possible.

Our scientific team supports each project with precision and responsiveness, in order to meet the specific requirements of each client.