Colchicine (alkaloid) dosage

Colchicine is an alkaloid too often associated with risks of acute toxicity, extracted mainly from the colchicum ( Colchicum autumnale ). Historically used in herbal medicine at low doses for its anti-inflammatory effects, it is now closely monitored in herbal preparations.

Colchicine dosage is essential to ensure the safety of formulations, particularly in plant extracts, food supplements, herbal teas, and colchicum-based products. The accidental or deliberate presence of colchicine in consumable products must be rigorously controlled.

Objectives of the analysis

• Evaluate the colchicine content in extracts or raw materials
• Check compliance with regulatory safety thresholds
• Identify contamination in plant products
• Secure herbal products or supplements based on colchicum
• Preventing the risks of acute poisoning linked to poor botanical identification

Analytical method

The analysis is performed by high-performance liquid chromatography (HPLC) or LC-MS/MS, two reliable methods for detecting and quantifying colchicine at trace levels. Coupling to mass spectrometry allows for maximum specificity even in complex matrices, such as plant powders or concentrated extracts.

Frequently analyzed matrices

• Hydroalcoholic extracts of colchicum
• Dried medicinal plants
• Herbal teas or traditional preparations
• Food supplements containing alkaloids
• Raw materials for phytotherapeutic use

Industrial applications

• Quality control of botanical batches containing colchicum
• Detection of cross-contamination between plants
• Regulatory security of plant formulations
• Toxicological assessment for marketing
• Compliance verification for distributors of medicinal plants

Why entrust your analyses to YesWeLab?

YesWeLab supports you in your plant extract security and regulatory compliance projects. Thanks to our network of ISO 17025-accredited partner laboratories, we offer customized services for the determination of alkaloids, including colchicine, with rapid turnaround times and complete traceability.

Our experts will guide you towards the most suitable analysis method according to your objectives: batch release, labeling verification, new product development or toxicological risk assessment.

Recommended internal links

To complete your analytical approach, also consult:

• Cinchonine (quinoline alkaloid) dosage : plant alkaloid used in herbal medicine
• Beta-carboline (indole alkaloid MTCA) assay : neuroactive tracer to monitor in fermented extracts
• Diosmetin (flavone) dosage : complementary analysis in medicinal plant extracts

Expert service for your botanical extracts

Since 2020, YesWeLab has been facilitating access to specialized analyses in the field of medicinal plants, natural extracts, and nutraceutical ingredients. Whether you are a formulator, manufacturer, or distributor, we support you in ensuring the reliability of your products and meeting the demands of the French and European markets.

Need a quote or customized analytical support? Contact our scientific team today.