Catalpol (iridoid glycoside) assay

Catalpol is an iridoid glycoside naturally present in several medicinal plants, notably Rehmannia glutinosa , species of the genus Plantago , and Digitalis . Sought after for its antioxidant, neuroprotective, anti-inflammatory, and tonic properties, it is among the active markers in plant extracts intended for the nutraceutical, cosmetic, and functional food sectors. As a reference molecule, its concentration directly determines the claimed value and efficacy of an extract.

Why measure catalpol?
Catalpol measurement ensures the quality, standardization, and efficacy of extracts containing it. For manufacturers, it addresses several key issues: standardizing an extract's active ingredient content, ensuring batch-to-batch consistency, verifying raw materials upon receipt, and substantiating claims while meeting regulatory requirements. Reliable catalpol quantification thus guarantees traceability and builds trust for extract buyers.

What analytical methods are used?
Analysis is primarily performed by liquid chromatography coupled with mass spectrometry (LC-MS) or by high-performance liquid chromatography (HPLC or UPLC), with UV or MS detection depending on the required sensitivity level. LC-MS is preferred for low concentrations or complex matrices, while HPLC-UV is suitable for sufficiently concentrated extracts. The assay can be adapted to a variety of plant matrices: powders, fluid extracts, solid preparations, or complex formulations.

Our expertise extends to bioactive plant compounds.
Catalpol is part of the large family of plant secondary metabolites that we regularly analyze. If you work on extract characterization, discover our related analyses: flavonoid analysis,polyphenol analysis , and isoflavone analysis, all using similar chromatographic techniques. This service primarily serves the nutraceutical and plant.

Why choose YesWeLab?
At YesWeLab, we collaborate with a rigorously selected network of laboratories, most of which are certified and/or accredited (ISO 17025, COFRAC). These laboratories are chosen based on your specific needs, the matrices to be analyzed, and the required analytical techniques or methods. If you have any particular requirements, please do not hesitate to specify them in your request: our scientific team will do everything possible to respond accurately and promptly. Since 2020, numerous manufacturers, distributors, and engineering firms have entrusted us with the management of their analyses, sending us their samples through our digital platform. To learn more or submit a specific request, contact our team today.